IRF: Institutional Repository FHNW
Willkommen auf der Publikations- und Forschungsdatenbank der Fachhochschule Nordwestschweiz FHNW.
Das IRF ist das digitale Repositorium der FHNW. Es enthält Publikationen, studentische Arbeiten und Projekte.
Weitere Informationen finden Sie im IRF-Handbuch.
Bereiche im IRF
Wählen Sie einen Bereich, um in den enthaltenen Sammlungen zu stöbern.
- APS FHNW
- HABG FHNW
- HGK Basel FHNW
- HSI FHNW
- HLS FHNW
- HSM Basel FHNW
- HSA FHNW
- HTU FHNW
- HSW FHNW
- PH FHNW
Neuzugänge
Stärke der Sozialen Arbeit in Krisen – der Ukrainekrieg
(09.08.2022) Jastrzebska, Maria Bernadetta
10 - Elektronische-/ Webpublikation
Clinical hurdles for curcumin and piperine nanoparticles in prostate cancer treatment. a bridge too far or a path to clinical reality?
(Taylor & Francis, 2026) Yakubu, Jibira; Tagit, Oya; Pandey, Amit V.
While nano-encapsulation enhances the therapeutic index of curcumin, clinical translation remains stalled by a reliance on passive targeting and insufficient manufacturing scalability. Future success depends on shifting from 'beaker' synthesis to microfluidic production (Quality by Design) and adopting active targeting (e.g. PSMA-directed delivery) to penetrate the prostate stroma. Without these strategic pivots and biomarker-driven trials, CPNs risk remaining an academic curiosity rather than evolving into a viable clinical intervention.
01A - Beitrag in wissenschaftlicher Zeitschrift
Beyond building structure. Estimating the material stock of mechanical, electrical and plumbing systems
(MDPI, 2026) Xiong, Shuyan; Krych, Kamila; Zea, Edwin; Habert, Guillaume
Current national-scale building stock models mainly focus on structural materials, overlooking the significant resource potential of Mechanical, Electrical, and Plumbing (MEP) systems. These systems are resource-intensive and contain standardized components with high-value materials such as copper and steel, yet their potential remains largely untapped due to fragmented data. This study introduces the novel systematic framework to estimate MEP components at high granularity and national scale. It integrates harmonized public data, machine-learning imputation (>90% accuracy under sparse conditions), and parametric rules reflecting building type, energy system, and construction decade. A Swiss case study yields scalable material stock estimates and lifespan-based turnover projections, showing strong consistency with existing GHG benchmarks. The framework highlights contrasting patterns across regions and building types, indicating where policy and industry can upscale reuse and recovery. Its modular design enables transferability and integration with circular economy planning and material-efficiency targets.
01A - Beitrag in wissenschaftlicher Zeitschrift
Ocular thermography and clinical measurements in symptomatic and asymptomatic soft contact lens wearers
(Wiley, 2024) Moghadas, Maryam; Nosch, Daniela; Käser, Emanuele; Klostermeier, Jennifer; Santer, Verena; Demian, Paul; Bertolini, Giovanni; Lamrani, Mouad
Significance
Symptoms of dryness and discomfort are the main reasons for contact lens dropout. Clinical tests for this purpose are invasive or subjective. Ocular thermography may help to assess the ocular discomfort and dryness in a noninvasive and objective manner.
Purpose
This study aimed to investigate the relationship of ocular thermography with clinical measurements in habitual symptomatic and asymptomatic soft contact lens wearers.
Methods
Forty habitual contact lens wearers were evaluated in two age‐ and gender‐matched asymptomatic and symptomatic groups (Contact Lens Discomfort Questionnaire scores ≤8 and ≥14, respectively). Clinical measurements took place during visit 1 (with contact lens in situ and after contact lens removal) and at baseline after a 2‐week washout period (visit 2). The Ocular Surface Disease Index (OSDI) questionnaire, noninvasive tear breakup time, bulbar conjunctival hyperemia, and corneal staining were assessed. Thermal cooling rate was computed in the central and lower cornea during natural blinking (30 s) and sustained eye opening (10 s).
Results
Dry eye symptoms (OSDI score) were significantly higher in the symptomatic group during contact lens wear (p<0.001) and at baseline (p = 0.001). Thermal cooling rate was significantly higher in the symptomatic group in the lower cornea (10 s, p=0.013) with the contact lens in situ and in the central cornea (30 s, p=0.045) after contact lens removal. At baseline, dry eye symptoms (OSDI score) significantly correlated with cooling rate in the central cornea region for the symptomatic group (30 s, r = −0.5, p=0.03; 10 s, r = −0.63, p=0.005). Noninvasive tear breakup time correlated with cooling rate in the central cornea region at baseline in the symptomatic group (30 s, r = 0.6, p=0.005; 10 s, r = 0.55, p=0.018). Cooling rate in the central cornea region (10‐s duration, p<0.0001) and noninvasive tear breakup time (p<0.0001) were identified as significant predictor variables for dry eye symptoms at baseline.
Conclusions
Noninvasive tear breakup time and thermal cooling rate were identified as significant predictor variables for contact lens–induced dry eye. These findings may suggest the potential for the additional application of ocular thermography in the evaluation of contact lens discomfort.
01A - Beitrag in wissenschaftlicher Zeitschrift
Occupational health risks and fate of chromium in sewage treatment co-treating tannery effluent
(Taylor & Francis, 29.10.2025) Villarreal, Karoll Michelle Cedeño; Furlong, Claire; Breitenmoser, Lena; Hooijmans, Christine Maria
This study investigated chromium (Cr) concentrations and fate across processes at a sewage treatment plant (STP) co-treating tannery effluent and assessed health risks for STP workers and farmers using the effluent for irrigation. Two novel secondary treatments, an IPC membrane and a modified constructed wetland, were evaluated as a mitigation method. Methods combined key informant interviews (n = 4), observations (n = 4), Cr analyses (n = 132) and a mass balance approach to track the fate of Cr. Total Cr in the STP influent ranged from 2.49 to 14.95 mg/L, while hexavalent Cr was <100µg/L. Primary sludge contained high total Cr (8,672 to 17,525 mg/kgDM) and hexavalent Cr (0.07 to 0.67 mg/kgDM). Final effluents from the novel and conventional treatments met the Indian discharge standards for total Cr (2 mg/L) and hexavalent Cr (0.1 mg/L). Risk assessment identified three high-risk activities for STP workers, all related to skin contact during primary sludge handling. Farmers irrigated with mixed STP and common effluent treatment plant (CETP) effluent ;the Cr in the CETP effluent was 16 times higher than the STP effluent. The novel technologies did not lower the risks, as they did not address sludge management or CETP effluent quality. Targeted controls for sludge management and coordinated action on CETP discharges are therefore critical.
01A - Beitrag in wissenschaftlicher Zeitschrift