• Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells 

      Alam, Shahidul; Anugraham, Merrina; Huang, Yen-Lin; Kohler, Reto; Hettich, Timm; Winkelbach, Katharina; Grether, Yasmin; Nunez Lopez, Monica; Khasbiullina, Nailia; Bovin, Nicolai V.; Schlotterbeck, Götz; Jacob, Francis (2017-03-30)
      Scientific Reports
      The (neo-) lacto series glycosphingolipids (nsGSLs) comprise of glycan epitopes that are present as blood group antigens, act as primary receptors for human pathogens and are also increasingly associated with malignant ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin
    • Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients 

      Kohler, Reto; Anugraham, Merrina; Nunez Lopez, Monica; Xiao, Christina; Schoetzau, Andreas; Hettich, Timm; Schlotterbeck, Götz; Fedier, André; Jacob, Francis; Heinzelmann-Schwarz, Viola (2016-07-12)
      Bisecting GlcNAc on N-glycoproteins is described in E-cadherin-, EGF-, Wnt- and integrin- cancer-associated signaling pathways. However, the mechanisms regulating bisecting GlcNAc expression are not clear. Bisecting ...
      01A - Beitrag in wissenschaftlicher Zeitschrift