Auflistung nach Autor/Autorin "Zabela, Volha"
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GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding
Zabela, Volha; Hettich, Timm; Schlotterbeck, Götz; Wimmer, Laurin; Mihovilovic D., Marko; Guillet, Fabrice; Belkacem, Bouaita; Shevchenko, Bénédicte; Hamburger, Matthias; Oufir, Mouhssin (2017-12)Journal of Chromatography BIn a screening of natural products for allosteric modulators of GABAA receptors (γ-aminobutyric acid type A receptor), piperine was identified as a compound targeting a benzodiazepine-independent binding site. Given that ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Pharmacokinetics of dietary kaempferol and its metabolite 4-hydroxyphenylacetic acid in rats
Zabela, Volha; Sampath, Chethan; Oufir, Mouhssin; Moradi-Afrapoli, Fahimeh; Butterweck, Veronika; Hamburger, Matthias (2016-12)FitoterapiaSCOPE: Kaempferol is a major flavonoid in the human diet and in medicinal plants. The compound exerts anxiolytic activity when administered orally in mice, while no behavioural changes were observed upon intraperitoneal ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Validation of UHPLC–MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies
Moradi-Afrapoli, Fahimeh; Oufir, Mouhssin; Walter, Fruzsina R.; Deli, Maria A.; Smiesko, Martin; Zabela, Volha; Butterweck, Veronika; Hamburger, Matthias (2016-09-05)Journal of Pharmaceutical and Biomedical Analysis01A - Beitrag in wissenschaftlicher Zeitschrift