Auflistung nach Autor/Autorin "Akbar, Rahmad"

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    • A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding 

      Miho, Enkelejda; Akbar, Rahmad; Pavlovic, Milena; Snapkov, Igor; Slabodkin, Andrei; Scheffer, Lonneke; Haff, Ingrid Hobaed; Tryslew Haug, Dag Trygve; Lund-Johanson, Fridtjof; Safonova, Yana; Greiff, Victor; Robert, Philippe; Jeliazkov, Jeliazko; Weber, Cedric; Sandve, Geir (2021-03-16)
      Cell Reports
      Antibody-antigen binding relies on the specific interaction of amino acids at the paratope-epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo antibody and (neo-)epitope design. ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin

    • Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction 

      Robert, Philippe A.; Akbar, Rahmad; Pavlović, Milena; Widrich, Michael; Snapkov, Igor; Slabodkin, Andrei; Chernigovskaya, Maria; Scheffer, Lonneke; Smorodina, Eva; Rawat, Puneet; Mehta, Brij Bhushan; Vu, Mai Ha; Mathisen, Ingvild Frøberg; Prósz, Aurél; Abram, Krzysztof; Olar, Axel; Miho, Enkelejda; Haug, Dag Trygve Tryslew; Lund-Johansen, Fridtjof; Hochreiter, Sepp; Hobæk Haff, Ingrid; Klambauer, Günter; Sandve, Geir Kjetil; Greiff, Victor (2022-12-19)
      Nature Computational Science
      Machine learning (ML) is a key technology for accurate prediction of antibody–antigen binding. Two orthogonal problems hinder the application of ML to antibody-specificity prediction and the benchmarking thereof: the lack ...
      01A - Beitrag in wissenschaftlicher Zeitschrift