Auflistung nach Autor/Autorin "Schönenberger, Monica"
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A new polymer/lipid system for hot-melt extrusion by designing a microstructure on an inorganic carrier (Poster)
Adler, Camille; Teleki, Alexandra; Kuentz, Martin; Schönenberger, Monica (2016)06 - Präsentation -
Early stages of drug crystallization from amorphous solid dispersion via fractal analysis based on chemical imaging
Kuentz, Martin; Abreu-Villela, Renata; Schönenberger, Monica; Caraballo, Isidoro (2018-12)European Journal of Pharmaceutics and BiopharmaceuticsEarly stages of crystallization from amorphous solid dispersion (ASD) are typically not detected by means of standard methods like powder X-ray diffraction (XRPD). The aim of this study is therefore to evaluate if fractal ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Flow-through cross-polarized imaging as a new tool to overcome the analytical sensitivity challenges of a low-dose crystalline compound in a lipid matrix
Adler, Camille; Schönenberger, Monica; Teleki, Alexandra; Leuenberger, Bruno; Kuentz, Martin (2015-11-10)Journal of Pharmaceutical and Biomedical AnalysisAssessing the physical state of a low-dose active compound in a solid lipid or polymer matrix is analytically challenging, especially if the matrix exhibits some crystallinity. The aim of this study was first to compare ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Modified Polymer Matrix in Pharmaceutical Hot Melt Extrusion by Molecular Interactions with a Carboxylic Coformer
Ditzinger, Felix; Scherer, Uta Maria; Schönenberger, Monica; Holm, Rene; Kuentz, Martin (2019)Molecular PharmaceuticsHot melt extrusion (HME) has become an essential technology to cope with an increasing number of poorly soluble drug candidates. However, there is only a limited choice of pharmaceutical polymers for obtaining suitable ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion
Adler, Camille; Schönenberger, Monica; Teleki, Alexandra; Kuentz, Martin (2016-02-29)International Journal of PharmaceuticsAmorphous solid dispersions have for many years been a focus in oral formulations, especially in combination with a hot-melt extrusion process. The present work targets a novel approach with a system based on a fatty acid, ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Temperature-Induced Surface Effects on Drug Nanosuspensions
Aleandri, Simone; Schönenberger, Monica; Niederquell, Andreas; Kuentz, Martin (2018-02)Pharmaceutical ResearchPurpose The trial-and-error approach is still predominantly used in pharmaceutical development of nanosuspensions. Physicochemical dispersion stability is a primary focus and therefore, various analytical bulk methods are ...01 - Zeitschriftenartikel, Journalartikel oder Magazin