• Caco-2 Permeability Studies and In Vitro hERG Liability Assessment of Tryptanthrin and Indolinone 

      Jähne, Evelyn A.; Eigenmann, Daniela E.; Moradi-Afrapoli, Fahimeh; Verjee, Sheela; Butterweck, Veronika; Hebeisen, Simon; Hettich, Timm; Schlotterbeck, Götz; Smiesko, Martin; Hamburger, Matthias; Oufir, Mouhssin (2016)
      Planta Medica
      Tryptanthrin and (E,​Z)​-​3-​(4-​hydroxy-​3,​5-​dimethoxybenzylidene)​indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-​inflammatory and antiallergic alkaloids, and shown to inhibit COX-​2, ...
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