Schlotterbeck, Götz

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Schlotterbeck
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Götz
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Schlotterbeck, Götz

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Thema: 600 - Technik, Medizin, angewandte Wissenschaften ×

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  • Vorschaubild nicht verfügbar
    Publikation
    Determination of active ingredients in formulated plant protection products by UHPLC-UV/MS
    (Springer, 04.10.2022) Erdin, Yves; Schlotterbeck, Götz; Mink, Christian [in: Journal of Consumer Protection and Food Safety]
    The market for plant protection products (PPPs) is one of the most regulated. With increasing regulations for registering PPPs, its requirements take more effort and more testing. Meanwhile, there is also an increasing market for illegal PPPs. While legally registered PPPs are thoroughly tested and documented, illegal PPPs are sold upfront without any testing (e.g., tox, aqua tox, eco tox). This bears additional risk for the users, the ecosystem and the public. There are many well established analytical methods and protocols to analyse soil, plant products as well as for food and beverage, but less for PPPs. Many methods need laborious sample preparation and extraction steps like QuEChERS and/or advanced mass spectrometry techniques. Here we present a method developed to identify active ingredients (AIs) which is easy to apply at relatively cheap costs and widely available instrumentation. It provides a straightforward set-up for sample preparation and analysis, without the need for elaborative sample preparation. The method validation showed sufficient linearity, repeatability and specificity to use this method for screening of samples taken from market control for counterfeit or cross contamination checks.
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    Absorption and metabolism of the natural sweeteners erythritol and xylitol in humans. A dose-ranging study
    (MDPI, 30.08.2022) Wölnerhanssen, Bettina K.; Meyer-Gerspach, Anne Christin; Bordier, Valentine; Teysseire, Valentine; Senner, Frank; Schlotterbeck, Götz; Drewe, Jürgen; Beglinger, Christoph [in: International Journal of Molecular Sciences]
    The natural sweeteners erythritol and xylitol might be helpful to reduce sugar consumption and therefore prevent obesity and diabetes. The aim of the present study was to determine the absorption and metabolization into erythronate of different concentrations of erythritol and xylitol. Seventeen healthy lean participants received intragastric solutions of 10, 25, or 50 g erythritol or 7, 17, or 35 g xylitol on three study days in a randomized order. The study was double blinded with respect to the doses administered. We assessed plasma concentrations of erythritol, xylitol, and erythronate at fixed time intervals after administration with gas chromatography-mass spectrometry. We found: (i) a dose-dependent and saturable absorption of erythritol, (ii) a very low absorption of xylitol, (iii) a dose-dependent metabolization of erythritol into erythronate, and (iv) no metabolization of xylitol into erythronate. The implications of the metabolization of erythritol into erythronate for human health remain to be determined and more research in this area is needed.
    01A - Beitrag in wissenschaftlicher Zeitschrift