Auflistung Hochschule für Life Sciences nach Titel
Anzeige der Einträge 1-20 von 36
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Caco-2 Permeability Studies and In Vitro hERG Liability Assessment of Tryptanthrin and Indolinone
(2016)Planta MedicaTryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory and antiallergic alkaloids, and shown to inhibit COX-2, ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations
(2019-03-12)European Journal of Pharmaceutical SciencesSupersaturating formulations are widely used to improve the oral bioavailability of poorly soluble drugs. However, supersaturated solutions are thermodynamically unstable and such formulations often must include a precipitation ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Can iron plaque affect Sb(III) and Sb(V) uptake by plants under hydroponic conditions
(2018-04)Environmental and Experimental BotanyAntimony (Sb) contamination of soils is of concern due to human activities such as recycling of Sb containing Pb acid batteries, shooting and mining. However Sb uptake by plants is poorly documented, especially when plants ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Can we estimate the critical micelle concentration of amphiphilic drug bases from molecular connectivity indices?
(2017)Pharmaceutical Development and TechnologySelf-aggregation of drugs is since many years an important topic in the pharmaceutical sciences. Drugs can aggregate similar to surfactants and thereby exhibit a critical micelle concentration (CMC). The present work focused ...01A - Beitrag in wissenschaftlicher Zeitschrift -
CaP bone‐like coating for fast osseointegration of dental implants
(2020-10-05)Clinical Oral Implants Research01A - Beitrag in wissenschaftlicher Zeitschrift -
Cell viability on titanium implant surfaces modified with antibacterial copper
(2015)European Cells and Materials04 - Beitrag Sammelband oder Konferenzschrift -
Characterization of a cotton-wool like composite bone graft material
(2022-07-18)Journal of Materials Science: Materials in MedicineBone graft materials are applied in patients to augment bone defects and enable the insertion of an implant in its ideal position. However, the currently available augmentation materials do not meet the requirements of ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Characterization of heavy metal toxicity in some plants and microorganisms—A preliminary approach for environmental bioremediation
(2020-01-13)New Biotechnology01A - Beitrag in wissenschaftlicher Zeitschrift -
Characterization of the housekeeping sortase from the human pathogen Propionibacterium acnes - first investigation of a class F sortase
(2019)Biochemical JournalSortase enzymes play an important role in Gram-positive bacteria. They are responsible for the covalent attachment of proteins to the surface of the bacteria and perform this task via a highly sequence-specific transpeptidation ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats
(2020-06-10)Pharmaceutical ResearchConclusion: Chase dosed LBF enhanced the in vivo bioavailability of nilotinib. Long chain lipids showed superior performance compared to medium chain lipids. Chase dosing appeared to prolong the absorption phase of the ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Clinical Characterisation of Eleven Lateral Flow Assays for Detection of COVID-19 Antibodies in a Population
(2020-08-25)medRxiv01A - Beitrag in wissenschaftlicher Zeitschrift -
Clinical necessity of multi-image based (4DMIB) optimization for targets affected by respiratory motion and treated with scanned particle therapy – A comprehensive review
(2022-02)Radiotherapy and Oncology4D multi-image-based (4D MIB) optimization is a form of robust optimization where different uncertainty scenarios, due to anatomy variations, are considered via multiple image sets (e.g., 4DCT). In this review, we focused ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Combining biorelevant in vitro and in silico tools to simulate and better understand the in vivo performance of a nano-sized formulation of aprepitant in the fasted and fed states
(2019-10-01)European Journal of Pharmaceutical SciencesINTRODUCTION: When developing bio-enabling formulations, innovative tools are required to understand and predict in vivo performance and may facilitate approval by regulatory authorities. EMEND® is an example of such a ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Combining Extracellular miRNA Determination with Microfluidic 3D Cell Cultures for the Assessment of Nephrotoxicity: a Proof of Concept Study
(2018-07)The AAPS JournalDrug-induced kidney injury is often observed in the clinics and can lead to long-term organ failure. In this work, we evaluated a novel in vitro system that aims at detecting whether compounds can cause renal proximal ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding
(2021-03-16)Cell ReportsAntibody-antigen binding relies on the specific interaction of amino acids at the paratope-epitope interface. The predictability of antibody-antigen binding is a prerequisite for de novo antibody and (neo-)epitope design. ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Comparative effects of nodularin and microcystin-LR in zebrafish: 1. Uptake by organic anion transporting polypeptide Oatp1d1 (Slco1d1)
(2016-02)Aquatic ToxicologyMicrocystin-LR (MC-LR) and nodularin are hepatotoxins produced by several cyanobacterial species. Their toxicity is based on active cellular uptake and subsequent inhibition of protein phosphatases PP1/2A, leading to ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Comparative Preliminary Evaluation of 2 In-stream Water Treatment Technologies for the Agricultural Reuse of Drainage Water in the Nile Delta
(2020-04-02)Integrated Environmental Assessment and Management01A - Beitrag in wissenschaftlicher Zeitschrift -
Comparing the antimicrobial activity of different commercially available cationic polymers
(2016-06-30)06 - Präsentation -
Comparison of methods to assess the integrity and separation efficiency of ultrafiltration membranes in wastewater reclamation processes
(2018-06)Journal Water Process EngineeringMembrane filtration is used in many water reuse applications, thanks to its high separation efficiency with regard to particles, bacteria, cysts and in the case of ultrafiltration even viruses. However, the separation ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Comparison of plasma ionization- and secondary electrospray ionization- high-resolution mass spectrometry for real-time breath analysis
(2022-02-23)ChimiaReal-time breath analysis by high-resolution mass spectrometry (HRMS) is a promising method to noninvasively retrieve relevant biochemical information. In this work, we conducted a head-to-head comparison of two ionization ...01A - Beitrag in wissenschaftlicher Zeitschrift