Zur Kurzanzeige

dc.contributor.authorFais, Stefano
dc.contributor.authorO'Driscoll, Lorraine
dc.contributor.authorBorras, Francesc E.
dc.contributor.authorBuzas, Edit
dc.contributor.authorCamussi, Giovanni
dc.contributor.authorCappello, Francesco
dc.contributor.authorCarvalho, Joana
dc.contributor.authorCordeiro da Silva, Anabela
dc.contributor.authorDel Portillo, Hernando
dc.contributor.authorEl Andaloussi, Samir
dc.contributor.authorFicko Trcek, Tanja
dc.contributor.authorFurlan, Roberto
dc.contributor.authorHendrix, An
dc.contributor.authorGursel, Ihsan
dc.contributor.authorKralj-Iglic, Veronika
dc.contributor.authorKaeffer, Bertrand
dc.contributor.authorKosanovic, Maja
dc.contributor.authorLekka, Marilena E.
dc.contributor.authorLipps, Georg
dc.contributor.authorLogozzi, Mariantonia
dc.contributor.authorMarcilla, Antonio
dc.contributor.authorSammar, Marei
dc.contributor.authorLlorente, Alicia
dc.contributor.authorNazarenko, Irina
dc.contributor.authorOliveira, Carla
dc.contributor.authorPocsfalvi, Gabriella
dc.contributor.authorRajendran, Lawrence
dc.contributor.authorRaposo, Graça
dc.contributor.authorRohde, Eva
dc.contributor.authorSiljander, Pia
dc.contributor.authorvan Niel, Guillaume
dc.contributor.authorVasconcelos, M. Helena
dc.contributor.authorYáñez-Mó, María
dc.contributor.authorYliperttula, Marjo L.
dc.contributor.authorZarovni, Natasa
dc.contributor.authorZavec, Apolonija Bedina
dc.contributor.authorGiebel, Bernd
dc.date.accessioned2016-10-21T10:29:40Z
dc.date.available2016-10-21T10:29:40Z
dc.date.issued2016-04-26
dc.identifier.issn1936-0851
dc.identifier.doi10.1021/acsnano.5b08015
dc.identifier.urihttp://hdl.handle.net/11654/23404
dc.description.abstractRecent research has demonstrated that all body fluids assessed contain substantial amts. of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid membranes contg. different membrane microdomains such as lipid rafts and caveolae. The most prominent representatives of these so-​called extracellular vesicles (EVs) are nanosized exosomes (70-​150 nm)​, which are derivs. of the endosomal system, and microvesicles (100-​1000 nm)​, which are produced by outward budding of the plasma membrane. Nanosized EVs are released by almost all cell types and mediate targeted intercellular communication under physiol. and pathophysiol. conditions. Contg. cell-​type-​specific signatures, EVs have been proposed as biomarkers in a variety of diseases. Furthermore, according to their phys. functions, EVs of selected cell types have been used as therapeutic agents in immune therapy, vaccination trials, regenerative medicine, and drug delivery. Undoubtedly, the rapidly emerging field of basic and applied EV research will significantly influence the biomedicinal landscape in the future. In this Perspective, we, a network of European scientists from clin., academic, and industry settings collaborating through the H2020 European Cooperation in Science and Technol. (COST) program European Network on Microvesicles and Exosomes in Health and Disease (ME-​HAD)​, demonstrate the high potential of nanosized EVs for both diagnostic and therapeutic (i.e., theranostic) areas of nanomedicine.
dc.description.urihttps://www.researchgate.net/publication/298420585_Evidence-Based_Clinical_Use_of_Nanoscale_Extracellular_Vesicles_in_Nanomedicine
dc.language.isoen
dc.relation.ispartofACS Nano
dc.accessRightsAnonymous
dc.subjectextracellular vesicles
dc.subjectnanomedicine
dc.titleEvidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine
dc.type01 - Zeitschriftenartikel, Journalartikel oder Magazin
dc.volume10
dc.issue4
dc.audienceScience
fhnw.publicationStatePublished
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publication
fhnw.InventedHereYes
fhnw.PublishedSwitzerlandNo
fhnw.pagination3886-3899
fhnw.IsStudentsWorkno
fhnw.publicationOnlineJa


Dateien zu dieser Ressource

DateienGrösseFormatAnzeige

Zu diesem Eintrag gibt es keine Dateien.

Der Eintrag erscheint in:

Zur Kurzanzeige