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Recent advances in understanding bacterial and archaeoeukaryotic primases

Lipps, Georg (2019-12)

Current Opinion in Structural Biology

DNA replication in all forms of life relies upon the initiation of synthesis on a single strand template by formation of a short oligonucleotide primer, which is subsequently elongated by DNA polymerases. Two structurally ...

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Stringent primer termination by an archaeo-eukaryotic DNA primase

Lipps, Georg; Bergsch, Jan; Devillier, Jean-Christophe; Jeschke, Gunnar (Frontiers, 2021-04-13)

Frontiers in Microbiology : Biology of archaea

Priming of single stranded templates is essential for DNA replication. In recent years, significant progress was made in understanding how DNA primase fulfils this fundamental function, particularly with regard to the ...