Auflistung Institut für Pharma Technology nach Autor/Autorin "Bennett-Lenane, Harriett"
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Artificial neural networks to predict the apparent degree of supersaturation in supersaturated lipid-based formulations. A pilot study
Bennett-Lenane, Harriett; O'Shea, Joseph; Murray, Jack; Ilie, Alexandra Roxana; Holm, Rene; Kuentz, Martin; Griffin, Brendan (2021-09-05)pharmaceuticsIn response to the increasing application of machine learning (ML) across many facets of pharmaceutical development, this pilot study investigated if ML, using artificial neural networks (ANNs), could predict the apparent ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
In Silico, In Vitro, and In Vivo evaluation of precipitation inhibitors in supersaturated lipid-based formulations of venetoclax
Koehl, Niklas; Henze, Laura; Bennett-Lenane, Harriett; Faisal, Waleed; Price, Daniel J.; Holm, Rene; Kuentz, Martin; Griffin, Brendan (2021-04-23)Molecular PharmaceuticsThe concept of using precipitation inhibitors (PIs) to sustain supersaturation is well established for amorphous formulations but less in the case of lipid-based formulations (LBF). This study applied a systematic in ...01 - Zeitschriftenartikel, Journalartikel oder Magazin