Auflistung Institut für Pharma Technology Nach Thema "lipid based formulation"
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Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats
(2020-06-10)Pharmaceutical ResearchConclusion: Chase dosed LBF enhanced the in vivo bioavailability of nilotinib. Long chain lipids showed superior performance compared to medium chain lipids. Chase dosing appeared to prolong the absorption phase of the ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
In Silico, In Vitro, and In Vivo evaluation of precipitation inhibitors in supersaturated lipid-based formulations of venetoclax
(2021-04-23)Molecular PharmaceuticsThe concept of using precipitation inhibitors (PIs) to sustain supersaturation is well established for amorphous formulations but less in the case of lipid-based formulations (LBF). This study applied a systematic in ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
New Insights into Using Lipid Based Suspensions for 'Brick Dust' Molecules: Case Study of Nilotinib
(2019-02-22)Pharmaceutical ResearchPurposeLipid suspensions have been shown to be a suitablebio-enabling formulation approach for highly lipophilic or‘grease ball’drug molecules, but studies on‘brick dust’drugsare lacking. This study explored the utility ...01 - Zeitschriftenartikel, Journalartikel oder Magazin
