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Hydroxypropyl Cellulose for Drug Precipitation Inhibition: From the Potential of Molecular Interactions to Performance Considering Microrheology
(American Chemical Society, 2022-01-10)
Molecular Pharmaceutics
There has been recent interest in using hydroxypropyl cellulose (HPC) for supersaturating drug formulations. This study investigated the potential for molecular HPC interactions with the model drug celecoxib by integrating ...
01A - Beitrag in wissenschaftlicher Zeitschrift
Advancing Raman model calibration for perfusion bioprocesses using spiked harvest libraries
(Wiley, 2022-08-07)
Biotechnology Journal
Background
Raman spectroscopy has gained popularity to monitor multiple process indicators simultaneously in biopharmaceutical processes. However, robust and specific model calibration remains a challenge due to insufficient ...
01A - Beitrag in wissenschaftlicher Zeitschrift
Evaluation of gravitational consolidation of binary powder mixtures by modified Heckel equation
(Elsevier, 2022)
Powder Technology
Consolidation of powders by tapping is an important quality test but it is time and material consuming, which encourages the use of mathematical modelling. This article aims to study this gravitational consolidation dynamics ...
01A - Beitrag in wissenschaftlicher Zeitschrift