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Effects of Silk Degumming Process on Physicochemical, Tensile, and Optical Properties of Regenerated Silk Fibroin
(2018-09)
Macromolecular Materials and Engineering
Sericin removal from silk (degumming) affects material characteristics of silk fibroin (SF). Sodium carbonate is most commonly used for degumming, but numerous alternative methods are available. Herein, a systematic ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Surface modification of nanofibrous matrices via layer-by-layer functionalized silk assembly for mitigating the foreign body reaction
(2018-05)
Biomaterials
The inherent hydrophobicity and large surface area of electrospun synthetic polymeric scaffolds often cause non-specific protein adsorption, thereby influencing macrophage functions and eventually leading to fibrosis at ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Influence of salt type and ionic strength on self-assembly of dextran sulfate-ciprofloxacin nanoplexes
(Elsevier, 2015)
International Journal of Pharmaceutics
We evaluated an analytical setup to identify optimal preparation conditions for nanoplex formation of small molecule drugs and polyelectrolytes using ciprofloxacin (CIP) and dextran sulfate (DS) as model compounds. The ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Controlled, localized delivery of macromolecular drugs through composite design and matrix modification
(2018-11)
06 - Präsentation
Matrix Metalloprotease Triggered Bioresponsive Drug Delivery Systems–Design, Synthesis and Application
(2018-10)
European Journal of Pharmaceutics and Biopharmaceutics
Engineering of drug delivery systems has evolved in recent decades from comparably simple designs that merely controlled drug release to complex, often multistage systems that respond to multiple biological or environmental ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Container Closure Integrity Testing of Prefilled Syringes,
(2018-08)
Journal of Pharmaceutical Sciences
Prefilled syringes (PFSs) are increasingly preferred over vials as container closure systems (CCSs) for injectable drug products when facilitated or self-administration is required. However, PFSs are more complex compared ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes
(2018-05)
PDA journal of pharmaceutical science and technology
The silicone lubricant layer in prefilled syringes has been investigated with regards to siliconization process performance, prefilled syringe functionality, and drug product attributes, such as subvisible particle levels, ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Application of natural and semi-synthetic polymers for the delivery of sensitive drugs
(Taylor & Francis, 2015-02)
International Materials Reviews
Abstract
This review summarises recent developments in the application of natural and semi-synthetic polymers for the delivery of sensitive drugs. Peptides, proteins and nucleic acids are drugs of increasing relevance ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Simple and rapid high performance liquid chromatography method for the determination of polidocanol as bulk product and in pharmaceutical polymer matrices using charged aerosol detection
(Elsevier, 2015-02)
Journal of Pharmaceutical and Biomedical Analysis
Currently, neither the European nor the United States Pharmacopoeia provide a method for the determination of polidocanol (PD) content despite the fact that PD, besides being an excipient, is also used as an active ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin