Suche
Anzeige der Einträge 1-10 von 135
Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across Permeapad Ⓡ membrane and in vivo absorption
(2020-07-03)
European Journal of Pharmaceutical Sciences
Supersaturated lipid-based drug delivery systems have recently been investigated for oral administration for a variety of lipophilic drugs and have shown either equivalent or superior oral bioavailability compared to ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Exploring the cocrystal landscape of posaconazole by combining high-throughput screening experimentation with computational chemistry
(American Chemical Society, 2022-12-23)
Crystal Growth & Design
The development of multicomponent crystal forms, such as cocrystals, represents a means to enhance the dissolution and absorption properties of poorly water-soluble drug compounds. However, the successful discovery of new ...
01A - Beitrag in wissenschaftlicher Zeitschrift
Mechanistic aspects of drug loading in liquisolid systems with hydrophilic lipid-based mixtures
(2020-01-30)
International Journal of Pharmaceutics
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Exploring the Impact of Surfactant Type and Digestion: Highly Digestible Surfactants Improve Oral Bioavailability of Nilotinib
(2020-09-08)
Molecular Pharmaceutics
The scientific rationale for selection of the surfactant type during oral formulation development requires an in-depth understanding of the interplay between surfactant characteristics and biopharmaceutical factors. ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax
(2020-06-18)
Pharmaceutics
Increasing numbers of beyond Rule-of-Five drugs are emerging from discovery pipelines, generating a need for bio-enabling formulation approaches, such as lipid-based formulations (LBF), to ensure maximal in vivo exposure. ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations
(2020-08-21)
Molecular Pharmaceutics
The absence of an intestinal absorption sink is a significant weakness of standard in vitro lipolysis methods, potentially leading to poor prediction of in vivo performance and an overestimation of drug precipitation. In ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Broadband Diffusing Wave Spectroscopy Reveals Microstructuring of Polymer–Drug System
(2020-04-16)
Crystal Growth & Design
01 - Zeitschriftenartikel, Journalartikel oder Magazin
Use of additives in particle engineering of spray-dried nanosuspensions
(2015)
06 - Präsentation
Partial Solvation Parameters of Drugs as a New Thermodynamic Tool for Pharmaceutics
(2019-01-04)
Pharmaceutics
Partial solvation parameters (PSP) have much in common with the Hansen solubility parameter or with a linear solvation energy relationship (LSER), but there are advantages based on the sound thermodynamic basis. It is, ...
01 - Zeitschriftenartikel, Journalartikel oder Magazin
SnO2 and ZnO Detectors of Hydrogen Peroxide Vapours
(2017)
06 - Präsentation