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dc.contributor.authorVogel, Dorian
dc.contributor.authorShah, Ashesh
dc.contributor.authorHemm-Ode, Simone
dc.date.accessioned2021-05-10T10:03:12Z
dc.date.available2021-05-10T10:03:12Z
dc.date.issued2020-04-25
dc.identifier.doi10.1016/j.nicl.2020.102271 Get
dc.identifier.urihttps://irf.fhnw.ch/handle/11654/32429
dc.description.abstractDeep brain stimulation (DBS) therapy requires extensive patient-specific planning prior to implantation to achieve optimal clinical outcomes. Collective analysis of patient’s brain images is promising in order to provide more systematic planning assistance. In this paper the design of a normalization pipeline using a group specific multi-modality iterative template creation process is presented. The focus was to compare the performance of a selection of freely available registration tools and select the best combination. The workflow was applied on 19 DBS patients with T1 and WAIR modality images available. Non-linear registrations were computed with ANTS, FNIRT and DRAMMS, using several settings from the literature. Registration accuracy was measured using single-expert labels of thalamic and subthalamic structures and their agreement across the group. The best performance was provided by ANTS using the High Variance settings published elsewhere. Neither FNIRT nor DRAMMS reached the level of performance of ANTS. The resulting normalized definition of anatomical structures were used to propose an atlas of the diencephalon region defining 58 structures using data from 19 patients.en_US
dc.description.urihttps://www.sciencedirect.com/science/article/pii/S221315822030108Xen_US
dc.language.isoenen_US
dc.relation.ispartofNeuroImage: Clinicalen_US
dc.accessRightsAnonymous*
dc.subjectDeep brain stimulation (DBS)en_US
dc.subjectPatient normalizationen_US
dc.subjectTemplate Group analysisen_US
dc.subjectImage registrationen_US
dc.subjectThalamusen_US
dc.subjectAtlasen_US
dc.titleAnatomical brain structures normalization for deep brain stimulation in movement disordersen_US
dc.type01 - Zeitschriftenartikel, Journalartikel oder Magazin*
dc.volume27en_US
dc.audienceScienceen_US
fhnw.publicationStatePublisheden_US
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publicationen_US
fhnw.InventedHereYesen_US
fhnw.PublishedSwitzerlandYesen_US
fhnw.IsStudentsWorknoen_US
fhnw.publicationOnlineJaen_US


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