Toothpastes with enzymes support gum health and reduce plaque formation
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Autor:innen
Paque, Pune
Schmidlin, Patrick
Wiedemeier, Daniel
Wegehaupt, Florian
Burrer, Phoebe
Körner, Philipp
Deari, Shengjile
Attin, Thomas
Autor:in (Körperschaft)
Publikationsdatum
19.01.2021
Typ der Arbeit
Studiengang
Typ
01A - Beitrag in wissenschaftlicher Zeitschrift
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Übergeordnetes Werk
International Journal of Environmental Research and Public Health
Themenheft
DOI der Originalpublikation
Link
Reihe / Serie
Reihennummer
Jahrgang / Band
18
Ausgabe / Nummer
835
Seiten / Dauer
1-14
Patentnummer
Verlag / Herausgebende Institution
MDPI
Verlagsort / Veranstaltungsort
Basel
Auflage
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-containing toothpastes with glucose oxidase and D-glucose with (C+) and without Citrox (C−) Citrox) were investigated in a clinical crossover trial (two slurries: sodium lauryl sulfate-containing (SLS), a toothpaste without SLS (reference), and water). Subjects (n = 20) abstained from toothbrushing for four days and rinsed with a toothpaste slurry. Bleeding on probing (BOP) and plaque indices (PI) were measured. A mixed linear model was used to statistically compare the slurries with respect to BOP and PI change. The in vitro bacterial growth-inhibiting evaluation showed the best results for SLS, followed by C+ and C−. The change in BOP and PI exhibited statistically significant differences to water rinsing (BOP; PI changes in % points (difference of the baseline and post-rinse values: water = 8.8%; 90.0%; C+ = −1.4%; 80.4%; SLS = 1.5%; 72.1%; reference = 0.8%; 77.5%; C− = −1.8%; 75.1%). All slurries exhibited anti-gingivitis and anti-plaque effects, resulting in a prophylactic benefit for limited-access regions during brushing.
Schlagwörter
Gingiva, Toothbrushing, Dentifrice, Prophylaxis, Prevention, Bacteria, Gingivitis, Low responder, High responder
Fachgebiet (DDC)
Veranstaltung
Startdatum der Ausstellung
Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
ISSN
1661-7827
1660-4601
1660-4601
Sprache
Englisch
Während FHNW Zugehörigkeit erstellt
Ja
Publikationsstatus
Veröffentlicht
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Gold
Lizenz
Zitation
PAQUE, Pune, Patrick SCHMIDLIN, Daniel WIEDEMEIER, Florian WEGEHAUPT, Phoebe BURRER, Philipp KÖRNER, Shengjile DEARI, Michel SCIOTTI und Thomas ATTIN, 2021. Toothpastes with enzymes support gum health and reduce plaque formation. International Journal of Environmental Research and Public Health. 19 Januar 2021. Bd. 18, Nr. 835, S. 1–14. DOI 10.3390/ijerph18020835. Verfügbar unter: https://doi.org/10.26041/fhnw-4127