Kind, LucyStevanovic, SabrinaWuttig, SinaWimberger, SandraHofer, JoëlleMüller, BertPieles, Uwe2017-06-222017-06-222017-03-270022-03451544-0591https://doi.org/10.1177/0022034517698419http://hdl.handle.net/11654/25070https://doi.org/10.26041/fhnw-1104Self-assembling β-sheet forming peptide P11-4 has shown potential in the treatment and prevention of dental caries by supporting tissue regeneration. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals. The hypothesis for the mode of action was that monomeric self-assembling peptide P11-4 diffuses into the subsurface lesion body and assembles therein into higher order fibrils, facilitating mineralization of the subsurface volume by mimicking the natural biomineralization of the tooth enamel.enenamel biomineralization/formationmicro–computed tomographyregenerationscanning electron microscopy (SEM)dentistryBiomimetic Remineralization of Carious Lesions by Self-Assembling Peptide01A - Beitrag in wissenschaftlicher Zeitschrift1-8