Fiave, Prosper AgbesiBoehringer, StephanGazdhar, AmiqGeiser, ThomasHradetzky, David2024-08-132024-08-1320131862-278X0013-558510.1515/bmt-2013-4041https://irf.fhnw.ch/handle/11654/46695Electric field accelerated plasmid droplets to permeate tissues has been demonstrated on cell culture and ex-vivo lung tissue of rats using enhanced green fluorescence protein reporter gene for transfection. This opens a window of opportunity to design an electrospray instrument usable within the working channel of bronchoscope to noninvasively treat idiopathic pulmonary fibrosis (IPF). We elaborate a concept and realized a device usable in the working channel of a flexible bronchoscope taking into account restrictions within typical bronchoscopy procedure.enGene delivery methodIdiopathic pulmonary fibriosisBronchoscopy600 - Technik, Medizin, angewandte Wissenschaften01A - Beitrag in wissenschaftlicher Zeitschrift