De Mesmaeker, AlainWendeborn, SebastianLebreton, Jaques2024-08-162024-08-161998-01-08WO9800434https://irf.fhnw.ch/handle/11654/46946https://doi.org/10.26041/fhnw-9970It is one object of the present invention to provide an oligonucleotide of formula (1): 5'-(U)n-3' in which U is an identical or different radical of a natural or a synthetic nucleoside, wherein the oligonucleotide comprises at least one modified nucleotide dimer comprising two nucleoside analogs connected via an amide-bond that has a certain configuration; the synthesis of these compounds and their use in pharmaceutical preparations.500 - Naturwissenschaften und Mathematik12 - Patent