Auflistung nach Autor/Autorin "Prestigiacomo, Vincenzo"
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3D human liver microtissues vs. 2D monolayer culture as an in vitro tool for compound testing
(2018-10)06 - Präsentation -
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Nrf2 protects stellate cells from Smad-dependent cell activation
(2018-07)PLOS ONEHepatic stellate cells (HSC) orchestrate the deposition of extracellular matrix (ECM) and are the primary effector of liver fibrosis. Several factors, including TGF-β1, PDGF and oxidative stress, have been shown to trigger ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Rat multicellular 3D liver microtissues to explore TGF-β1 induced effects
(2019-11-13)Journal of Pharmacological and Toxicological MethodsChronic liver damage can lead to fibrosis, encompassing hepatocellular injury, activation of Kupffer cells (KC), and activation of hepatic stellate cells (HSC). Inflammation and TGF-β1 are known mediators in the liver ...01A - Beitrag in wissenschaftlicher Zeitschrift -
The role of bile salts in cholestatic injury and fibrosis using a human 3D in vitro model
(2018-11)06 - Präsentation