Auflistung nach Autor/Autorin "Zhang, Kun"
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Activity of binary mixtures of drospirenone with progesterone and 17?-ethinylestradiol in vitro and in vivo
Rossier, Nadine Madeleine; Chew, Geraldine; Zhang, Kun; Riva, Francesco; Fent, Karl (2016-02-22)Aquatic ToxicologyDespite potential exposure of aquatic organisms to mixtures of steroid hormones, very little is known on their joint activity in fish. Drospirenone (DRS) is a new synthetic progestin used in contraceptive pills in combination ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (Danio rerio) at Low Concentrations
Zhao, Yanbin; Zhang, Kun; Fent, Karl (2016-09-12)Environmental Science & TechnologySynthetic corticosteroids may pose an environmental risk to fish. Here, we describe multiend point responses of adult zebrafish (8 months old) upon 21-day exposure to a commonly prescribed corticosteroid, fludrocortisone ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Determination of two progestin metabolites (17a-hydroxypregnanolone and pregnanediol) and different classes of steroids (androgens, estrogens, clorticosteroids, progestins) in rivers and wastewaters by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
Fent, Karl; Zhang, Kun (2018)Science of the Total EnvironmentA highly sensitive and robust method was developed for routine analysis of two progestin metabolites, 17α-hydroxypregnanolone (17OH-Δ5P) and pregnanediol (PD), and 31 other natural and synthetic steroids and related ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Environmental chemicals affect circadian rhythms. An underexplored effect influencing health and fitness in animals and humans
Zheng, Xuehan; Zhang, Kun; Zhao, Yanbin; Fent, Karl (2021-04)Environment InternationalCircadian rhythms control the life of virtually all organisms. They regulate numerous aspects ranging from cellular processes to reproduction and behavior. Besides the light-dark cycle, there are additional environmental ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Occurrence and ecotoxicological effects of free, conjugated, and halogenated steroids including 17a-hydroxypregnanolone and pregnanediol in Swiss watewater and surface water
Fent, Karl; Zhang, Kun; Zhao, Yanbin (2017)Environmental Science & TechnologyApart from estrogens, the occurrence and ecotoxicity of steroids in aquatic environments is poorly known. Here, we analyzed 33 steroids, including estrogens, androgens, progestins, and glucocorticoids, in hospital wastewaters, ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Regulation of zebrafish (Danio rerio) locomotor behavior and circadian rhythm network by environmental steroid hormones
Fent, Karl; Zhao, Yanbin; Zhang, Kun (2018-01)Environmental PollutionEnvironmental exposure of fish to steroid hormones through wastewater and agricultural runoff may pose a health risk. Thus far, ecotoxicological studies have largely been focused on the disruption of the sex hormone system, ...01A - Beitrag in wissenschaftlicher Zeitschrift -
Reproductive and transcriptional effects of the antiandrogenic progestin chlormadinone acetate in zebrafish (Danio rerio)
Zhang, Kun; Fent, Karl; Siegenthaler, Patricia Franziska; Zhao, Yanbin (2017)Environmental PollutionChlormadinone acetate (CMA) is a frequently used progestin with antiandrogenic activity in humans. Residues may enter the aquatic environment but potential adverse effects in fish are unknown. While our previous work focused ...01A - Beitrag in wissenschaftlicher Zeitschrift