Auflistung nach Autor/in "Sampath, C"

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Development and full validation of an UPLC-MS/MS method for the quantification of the plant-derived alkaloid indirubin in rat plasma

Jähne, EA; Sampath, C; Butterweck, Veronika; Hamburger, Matthias; Oufir, M (2016)

An UPLC-MS/MS method for the quantification of indirubin in lithium heparinized rat plasma was developed and validated according to current international guidelines. Indirubin was extracted from rat plasma by using Waters ...
Pharmacokinetics and in vitro blood-brain barrier screening of the plant-derived alkaloid tryptanthrin

Jähne, E; Eigenmann, D; Sampath, C; Butterweck, Veronika; Culot, M; Cecchelli, R; Gosselet, F; Walter, F. R.; Deli, MA; Smiesko, M; Hamburger, M; Oufir, M (2016)

The indolo[2,1-b]quinazoline alkaloid tryptanthrin was previously identified as a potent anti-inflammatory compound with a unique pharmacological profile. It is a potent inhibitor of cyclooxygenase-2, 5-lipooxygenase-catalyzed ...
Pharmacokinetics of dietary kaempferol and its metabolite 4-hydroxyphenylacetic acid in rats

Zabela, V; Sampath, C; Oufir, Mouhssin; Moradi-Afrapoli, Fahimeh; Butterweck, Veronika; Hamburger, Matthias (2016-12)

SCOPE: Kaempferol is a major flavonoid in the human diet and in medicinal plants. The compound exerts anxiolytic activity when administered orally in mice, while no behavioural changes were observed upon intraperitoneal ...