• Adaptive immune receptor repertoire (AIRR) community guide to TR and IG gene annotation 

      Babrak, Lmar; Marquez, Susanna; Busse, Christian; Lees, William; Miho, Enkelejda; Ohlin, Mats; Rosenfeld, Aaron; Stervbo, Ulrik; Watson, Corey; Schramm, Chaim (2022-05-28)
      Immunogenetics Methods and Protocols
      High-throughput sequencing of adaptive immune receptor repertoires (AIRR, i.e., IG and TR) has revolutionized the ability to carry out large-scale experiments to study the adaptive immune response. Since the method was ...
      04A - Beitrag Sammelband
    • Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences 

      Smakaj, Erand; Babrak, Lmar; Tosoni, Deniz David; Galli, Christa; Miho, Enkelejda (2019-12-24)
      01 - Zeitschriftenartikel, Journalartikel oder Magazin
    • Machine learning detects anti-DENV signatures in antibody repertoire sequences 

      Horst, Alexander; Smakaj, Erand; Natali, Eriberto; Tosoni, Deniz David; Babrak, Lmar; Meier, Patrick; Miho, Enkelejda (2021-10-11)
      Frontiers in Artificial Intelligence
      Dengue infection is a global threat. As of today, there is no universal dengue fever treatment or vaccines unreservedly recommended by the World Health Organization. The investigation of the specific immune response to ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin
    • Prospective artificial intelligence to dissect the dengue immune response and discover therapeutics 

      Natali, Eriberto; Babrak, Lmar; Miho, Enkelejda (2021-06-15)
      frontiers in immunology
      Dengue virus (DENV) poses a serious threat to global health as the causative agent of dengue fever. The virus is endemic in more than 128 countries resulting in approximately 390 million infection cases each year. Currently, ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin
    • RWD-Cockpit. Application for quality assessment of real-world data 

      Degen, Markus; Babrak, Lmar; Smakaj, Erand; Agac, Teyfik; Asprion, Petra; Grimberg, Frank; Van der Werf, Daan; Van Ginkel, Erwin Willem; Tosoni, Deniz David; Clay, Ieuan; Brodbeck, Dominique; Natali, Eriberto; Schkommodau, Erik; Miho, Enkelejda (2022-10-18)
      JMIR formative research
      Digital technologies are transforming the health care system. A large part of information is generated as real-world data (RWD). Data from electronic health records and digital biomarkers have the potential to reveal ...
      01A - Beitrag in wissenschaftlicher Zeitschrift
    • Single Cell Gene Expression analysis in a 3D microtissue liver model reveals cell type-specific responses to pro-fibrotic TGF-β1 stimulation 

      Messner, Catherine; Babrak, Lmar; Titolo, Gaia; Caj, Michaela; Miho, Enkelejda; Suter-Dick, Laura (2021-04-22)
      International Journal of Molecular Sciences
      3D cell culture systems are widely used to study disease mechanisms and therapeutic interventions. Multicellular liver microtissues (MTs) comprising HepaRG, hTERT-HSC and THP-1 maintain multicellular interactions and ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin
    • Traditional and Digital Biomarkers: Two Worlds Apart? 

      Babrak, Lmar; Miho, Enkelejda (2019)
      Digital Biomarkers
      The identification and application of biomarkers in the clinical and medical fields has an enor - mous impact on society. The increase of digital devices and the rise in popularity of health- related mobile apps has ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin