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Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations
(2020-08-21)
Molecular Pharmaceutics
The absence of an intestinal absorption sink is a significant weakness of standard in vitro lipolysis methods, potentially leading to poor prediction of in vivo performance and an overestimation of drug precipitation. In ...
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Trends in the Assessment of Drug Supersaturation and Precipitation In Vitro Using Lipid-Based Delivery Systems
(2016)
Journal of Pharmaceutical Sciences
The generation of drug supersaturation close to the absorptive site is an important mechanism of how several formulation technologies enhance oral absorption and bioavailability. Lipid-based formulations belong to the ...
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Permeation characteristics of hypericin across Caco-2 monolayers in presence of singe flavonoids, defined flavonoid mixtures or Hypericum extract matrix
(2017)
Journal of pharmacy and pharmacology
Objectives
The major aim of this study was to get a detailed understanding of the exposure and fate of hypericin in the Caco-2 cell system when combined with various flavonoids, mixtures of flavonoids or Hypericum ...
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Crystallographic, optical, and electronic properties of the Cs2AgBi1–xInxBr6 double perovskite. Understanding the fundamental photovoltaic efficiency challenges
(American Chemical Society, 2021-02-19)
ACS Energy Letters
We present a crystallographic and optoelectronic study of the double perovskite Cs2AgBi1–xInxBr6. From structural characterization we determine that the indium cation shrinks the lattice and shifts the cubic-to-tetragonal ...
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