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Antibacterial Active Glass
Targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) employing an enzymatic assay for γ-hydroxybutyric acid (GHB) in biofluids
Hypothesis An enzymatic assay for quantification of γ-hydroxybutyric acid (GHB) in biofluids can be employed for targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) in selected populations. ...
Epigenetic activation of MGAT3 and corresponding bisecting GlcNAc shortens the survival of cancer patients
Bisecting GlcNAc on N-glycoproteins is described in E-cadherin-, EGF-, Wnt- and integrin- cancer-associated signaling pathways. However, the mechanisms regulating bisecting GlcNAc expression are not clear. Bisecting ...
Supramolecular enzyme engineering in complex nanometer-thin biomimetic organosilica layers
The use of enzymes in industrial processes is often hampered by their limited stability under operational conditions. As enzymes' function and stability are directly correlated to their three-dimensional structure, ...
Enzyme Shielding in an Enzyme-thin and Soft Organosilica Layer
The fragile nature of most enzymes is a major hindrance to their use in industrial processes. Herein, we describe a synthetic chem. strategy to produce hybrid org./inorg. nanobiocatalysts; it exploits the self-assembly ...
Immobilization of an artificial imine reductase within silica nanoparticles improves its performances
Silica nanoparticles equipped with an artificial imine reductase (biotinylated iridium complex conjugated with streptavidin) display marked redn. activity toward cyclic imines and NAD. The method, based on immobilization ...