Auflistung Institut für Pharma Technology nach Autor/Autorin "Jähne, Evelyn A."

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    • Development and full validation of an UPLC-MS/MS method for the quantification of the plant-derived alkaloid indirubin in rat plasma 

      Jähne, Evelyn A.; Butterweck, Veronika; Hamburger, Matthias; Oufir, Mouhssin; Sampath, Chethan (2016)
      Journal of Pharmaceutical and Biomedical Analysis
      An UPLC-MS/MS method for the quantification of indirubin in lithium heparinized rat plasma was developed and validated according to current international guidelines. Indirubin was extracted from rat plasma by using Waters ...
      01A - Beitrag in wissenschaftlicher Zeitschrift

    • Pharmacokinetics and in vitro blood-brain barrier screening of the plant-derived alkaloid tryptanthrin 

      Jähne, Evelyn A.; Eigenmann, Daniela E.; Sampath, Chethan; Butterweck, Veronika; Culot, Maxime; Cecchelli, Roméo; Gosselet, Fabien; Walter, Fruzsina R.; Deli, Maria A.; Smiesko, Martin; Hamburger, Matthias; Oufir, Mouhssin (2016)
      Planta Medica
      The indolo[2,1-b]quinazoline alkaloid tryptanthrin was previously identified as a potent anti-inflammatory compound with a unique pharmacological profile. It is a potent inhibitor of cyclooxygenase-2, 5-lipooxygenase-catalyzed ...
      01A - Beitrag in wissenschaftlicher Zeitschrift