Auflistung Institut für Pharma Technology nach Titel

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    • Rapid determination of drug solubilization versus supersaturation in natural and digested lipids 

      Gautschi, Nicolas; Bergstroem, Christel; Kuentz, Martin (2016)
      International Journal of Pharmaceutics
      Lipid-​based formulations (LBFs) represent one of the successful formulation approaches that enable oral delivery of poorly water-​sol. drugs. This work presents a simple equil. approach based on soly. in lipids and their ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin

    • Rational selection of bio-enabling oral drug formulations. A PEARRL commentary 

      Kuentz, Martin; Kronseder, Christian; Holm, Rene; Saal, Christoph; Griffin, Brendan (2021-05)
      Journal of Pharmaceutical Sciences
      New drug candidates often require bio-enabling formation technologies such as lipid-based formulations, solid dispersions, or nanosized drug formulations. Development of such more sophisticated delivery systems generally ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin

    • A Relative Permittivity Approach for Fast Drug Solubility Screening of Solvents and Excipients in Lipid-Based Delivery 

      Niederquell, Andreas; Kuentz, Martin (2019)
      Journal of Pharmaceutical Sciences
      Drug solubility screening in solvents and lipids is central for the development of lipid-based formulations (LBFs), and any guidance to reduce the experimental workload would be highly desirable. Solubility parameters are ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin

    • Relevance of the theoretical critical pore radius in mesoporous silica for fast crystallizing drugs 

      Vraníková, Barbora; Niederquell, Andreas; Kuentz, Martin (2020-10-26)
      International Journal of Pharmaceutics
      Formulation of poorly water-soluble drugs with mesoporous silica has become a thriving field of pharmaceutics. The theoretical critical pore diameter has been introduced as a maximum value below which an undesired drug ...
      01 - Zeitschriftenartikel, Journalartikel oder Magazin