Auflistung Institut für Pharma Technology nach Titel
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Temperature-Induced Surface Effects on Drug Nanosuspensions
(2018-02)Pharmaceutical ResearchPurpose The trial-and-error approach is still predominantly used in pharmaceutical development of nanosuspensions. Physicochemical dispersion stability is a primary focus and therefore, various analytical bulk methods are ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics
(2015)Journal of Materials Chemistry B01 - Zeitschriftenartikel, Journalartikel oder Magazin -
The quest for exceptional drug solubilization in diluted surfactant solutions and consideration of residual solid state
(2017)European Journal of Pharmaceutical SciencesSolubility screening in different surfactant solutions is an important part of pharmaceutical profiling. A particular interest is in low surfactant concentrations that mimic the dilution of an oral dosage form. Despite of ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Theoretical Considerations of the Prigogine–Defay Ratio with Regard to the Glass-Forming Ability of Drugs from Undercooled Melts
(2016)Molecular PharmaceuticsDrug behavior in undercooled melts is highly important for pharmaceutics with regard to amorphous solid dispersions, and therefore, categories were recently introduced that differentiate glass formers (GFs) from other drugs ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Toward simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients
(2020-11-09)Drug Development and Industrial PharmacyObjective: This study aimed to systematically explore compositional effects for a series of lipid systems, on the in vitro drug solubilization and in vivo bioavailability of three poorly water-soluble drugs with different ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Towards a better understanding of solid dispersions in aqueous environment by a fluorescence quenching approach
(2018-10-25)Internation Journal of PharmaceuticsSolid dispersions (SDs) represent an important formulation technique to achieve supersaturation in gastro-intestinal fluids and to enhance absorption of poorly water-soluble drugs. Extensive research was leading to a rather ...01 - Zeitschriftenartikel, Journalartikel oder Magazin -
Trends in the Assessment of Drug Supersaturation and Precipitation In Vitro Using Lipid-Based Delivery Systems
(2016)Journal of Pharmaceutical SciencesThe generation of drug supersaturation close to the absorptive site is an important mechanism of how several formulation technologies enhance oral absorption and bioavailability. Lipid-based formulations belong to the ...01 - Zeitschriftenartikel, Journalartikel oder Magazin
