Auflistung Institut für Pharma Technology nach Titel

Ultra-sub-stoichiometric “Dynamic” Bioconjugation Reduces Viscosity by Disrupting Immunoglobulin Oligomerization

Gong, Yuhui; Niederquell, Andreas; Kuentz, Martin (2019-09-09)

Biomacromolecules

Monoclonal antibodies (mAb) are a major focus of the pharmaceutical industry, and polyclonal immunoglobulin G (IgG) therapy is used to treat a wide variety of health conditions. As some individuals require mAb/IgG therapy ...

01 - Zeitschriftenartikel, Journalartikel oder Magazin

Unexpected solubility enhancement of drug bases in presence of a dimethylaminoethyl methacrylate copolymer

Saal, Wiebke; Ross, Alfred; Wyttenbach, Nicole; Alsenz, Jochem; Kuentz, Martin (2017)

Molecular Pharmaceutics

The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with polymeric side chains. The latter type ...

01 - Zeitschriftenartikel, Journalartikel oder Magazin

Use of Additives in Particle Engineering of Spray - dried Nanosuspensions

Joost, Berndt; Simkova, Katerina; Stalder, Jasmin (2015)

06 - Präsentation

Use of additives in particle engineering of spray-dried nanosuspensions

Joost, Berndt; Simkova, Katerina; Stebler, Felix; Stalder, Jasmin (2015)

06 - Präsentation

Using Physiologically Based Pharmacokinetic (PBPK) Modelling to Gain Insights into the Effect of Physiological Factors on Oral Absorption in Paediatric Populations

Villiger, Angela; Stillhart, Cordula; Parrot, Neil; Kuentz, Martin (2016-07-08)

The AAPS Journal

Paediatric pharmaceutics has become an important topic, but currently, there is an incomplete knowledge of paediatric gastrointestinal physiology and adequate biopharmaceutical tools still have to be developed. The present ...

01 - Zeitschriftenartikel, Journalartikel oder Magazin