Nosch, Daniela

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Nosch
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Daniela
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Nosch, Daniela

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2013 - 20182
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Hochschule: Hochschule für Technik × Thema: cornea ×

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    Publikation
    Does air gas aesthesiometry generate a true mechanical stimulus for corneal sensitivity measurement?
    (Wiley, 01.03.2018) Nosch, Daniela; Pult, Heiko; Albon, Julie; Purslow, Christine; Murphy, Paul J [in: Clinical and Experimental Optometry]
    Aim of this study - to determine: (A) the stimulus temperature inducing no or least change in ocular surface temperature (OST), using the Belmonte Ocular Pain Meter (OPM); and (B) to evaluate if OST remains unchanged with different stimulus durations and airflow rates. A total of 14 subjects (mean age 25.14 ± 2.18 years) participated: (A) OST was recorded using an infrared camera (FLIR A310) during the presentation of airflow stimuli, at five temperatures, ambient temperature (AT) +5°C, +10°C, +15°C, +20°C and +30°C, using the OPM; and (B) OST measurements were repeated with two stimulus temperatures (AT +10°C and +15°C) while varying stimulus durations and airflow rates. Results: (A) Stimulus temperatures of AT +10°C and +15°C induced the least changes in OST (-0.20 ± 0.13°C and 0.08 ± 0.05°C). (B) OST changes were statistically significant with both stimulus temperatures and increased with increasing airflow rates (p < 0.001).
    01A - Beitrag in wissenschaftlicher Zeitschrift
  • Vorschaubild
    Publikation
    The accuracy of dynamic contour tonometry over soft contact lenses
    (Lippincott Williams & Wilkins, 02/2013) Gogniat, Fabrice; Steinegger, Daniela; Nosch, Daniela; Joos, Roland E; Goldschmidt, Michael [in: Optometry & Vision Science]
    Purpose. Dynamic contour tonometry (DCT) has been shown to measure the intraocular pressure (IOP) independently of corneal thickness. This study aimed to investigate if DCT remains accurate when the IOP measurement is taken over soft contact lenses (CLs) of different thicknesses and material characteristics. Methods. This was a prospective clinical study that included 42 patients. Subject age was 22 to 59 years (26.5 T 6.3 years). Intraocular pressure and ocular pulse amplitude (OPA) measurements were taken under topical anesthesia without CLs and over various daily disposable CLs with j0.50, +5.00, and j5.00 diopters (D) in hydrogel (Nelfilcon A) and in silicone hydrogel (Narafilcon A) materials. Results. No statistically significant differences were found when comparing the IOP measurements obtained using either of the different CL powers of j0.50 or j5.00 D, irrespective of which CL material was being used. However, the difference of 0.62mmHg observed when the Nelfilcon Awith a power of +5.00Dwas used turned out to be highly statistically significant (p = 0.0002), whereas the Narafilcon Awith the same power of +5.00 D, with a small difference of j0.16 mm Hg, was not. Regarding OPA measurements, no significant differences were found between measurements with and without CL neither for different materials nor for change in dioptrical power (F = 0, p = 1.000). Conclusions. This study showed good reliability of IOP and OPA measurements over CLs with varying thickness profiles and different soft materials when using the DCT. Only a small but statistically significant difference of 0.62mmHg was found for the IOP measurement with the hydrogel CL of +5.00 D compared with ‘‘no CL.’’
    01A - Beitrag in wissenschaftlicher Zeitschrift