Pekacka-Egli, Anna Maria

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Pekacka-Egli
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Anna Maria
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Anna Maria Pekacka-Egli

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2017 - 201952020 - 202316
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  • Vorschaubild nicht verfügbar
    Publikation
    Schluckstörungen im Alter. Diagnostik und Therapie in der Grundversorgung
    (Springer Medizin, 17.11.2023) Pekacka-Egli, Anna Maria; Bujan, Magdalena; Disko, Andreas; Lutz, Dietmar; Spielmanns, Marc; Kolbm, Benjamin; Bujanm Bartosz [in: Zeitschrift für Allgemeinmedizin]
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Clinical effects of pulmonary rehabilitation in very old patients with COPD
    (MDPI, 2023) Spielmanns, Marc; Schulze, Sofia-Theresia; Guenes, Erhan; Pekacka-Falkowska, Katarzyna; Windisch, Wolfram; Pekacka-Egli, Anna Maria [in: Journal of Clinical Medicine]
    Background: Pulmonary rehabilitation (PR) improves physical and mental performance as well as quality of life in patients with chronic obstructive pulmonary disease (COPD). However, data on outcomes in very old patients are insufficient. We analyzed whether the elderly with COPD benefit in a similar way to younger patients from participation in an inpatient PR according to the assessments usually collected. Methods: Data from 3173 patients with COPD were retrospectively analyzed. Patients were referred to PR at the Zurich RehaZentren, Switzerland, between January 2013 and December 2019. PR was performed 6 days per week with an average duration of 18.85 days. Functional Independence Measurement (FIM), Feeling Thermometer (FT), and 6-Minute Walk Test (6MWT) were recorded on admission and discharge. Results: In all age groups, the 6MWT and FT improved significantly. FIM results also showed a significant increase. The results of the different age groups showed no significant differences in percentage improvements according to the assessments that were considered. Conclusions: All patient groups with COPD, even the oldest (>85 years), benefited from PR regardless of their age and according to the assessments. Prospective studies are needed to support this hypothesis.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Pulmonary rehabilitation outcomes of post-acute COVID-19 patients during different waves of the pandemic
    (MDPI, 2023) Spielmanns, Marc; Schaer, Corina E.; Pekacka-Egli, Anna Maria; Spielmanns, Sabine; Ibish, Olberk; Gafina, Guzel; Stiube, Antonela; Hermann, Matthias [in: International Journal of Environmental Research and Public Health]
    (1) Background: Between the beginning of the coronavirus pandemic and summer 2022, we distinguished four pandemic waves, with different characteristics of the affected patients. This study investigated the impact of patient characteristics on the outcome of inpatient pulmonary rehabilitation (PR). (2) Methods: Using a prospective approach, the characteristics of post-acute COVID-19 patients of the different waves who participated in inpatient PR were compared based on their assessments and results collected as part of PR (Cumulative Illness Rating Scale (CIRS), six-minute walk test (6-MWT), Pulmonary Function Testing (PFT), and Functional Independent Measurement (FIM). (3) Results: A total of 483 patients were included in the analysis (Wave 1 n = 51, Wave 2 n = 202, Wave 3 n = 84, Wave 4 n = 146). Compared to Wave 3 + 4, patients of Wave 1 + 2 were older (69 vs. 63 years; p < 0.001), had a significantly lower CIRS (13.0 vs. 14.7 points; p = 0.004), had significant better PFT (FVC: 73 vs. 68%pred; p = 0.009; DLCOSB: 58 ± 18 vs. 50 ± 17%pred; p = 0.001), and showed significantly more comorbidities (2.0 vs. 1.6 n/pers.; p = 0.009). Wave 3 + 4 showed significantly greater improvements according to the 6-MWT (147 vs. 188 m; p < 0.001) and the FIM (5.6 vs. 21.1 points; p < 0.001). (4) Conclusions: Patients of the COVID-19 infection waves differed significantly according to their anthropometric data, incidence of comorbidities, and impact of the infection. All cohorts achieved clinically relevant and significant functional improvements during PR, with significant higher improvements in Wave 3 + 4.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD. A randomised controlled trial
    (BJM Group, 2022) Spielmanns, Marc; Gloeckl, Rainer; Jarosch, Inga; Leitl, Daniela; Schneeberger, Tessa; Boeselt, Tobias; Huber, Stephan; Kaur-Bollinger, Pawandeep; Ulm, Bernhard; Mueller, Claudia; Bjoerklund, Jonas; Spielmanns, Sabine; Windisch, Wolfram; Pekacka-Egli, Anna Maria; Koczulla, Andreas Rembert [in: Thorax]
    Background. Evidence suggests that patients with COPD struggle to maintain improved physical activity (PA) after completing pulmonary rehabilitation (PR). Smartphone applications (apps) providing a comprehensive training programme have conferred healthy benefits. This study was conducted to determine whether regular usage of an app maintains PA following PR. Patients with stage II–IV COPD were enrolled in a 6-month trial following PR. After the screening period, participants were randomised into the Kaia COPD app group (intervention group (IG)) or the control group (CG). The primary outcome was PA (daily steps), measured using an activity tracker. Secondary outcomes included the COPD Assessment Test (CAT), the Chronic Respiratory Disease Questionnaire (CRQ) and the 1 min Sit-to-Stand Test (STST).Methods Sixty participants completed the study. The median steps from baseline to 6 months were significantly different between the groups, in favour of the IG (−105.3, IQR −1970.1 to 2105.8, vs CG −1173.0, IQR −3813.1 to –93.8; p=0.007). CAT was significantly decreased in the IG (15.1±8.6 vs 19.7±6.4, p=0.02), whereas the CRQ subdomains for dyspnoea (4.5±1.7 vs 3.7±1.3, p=0.033) and fatigue (4.5±1.4 vs 3.5±1.3, p=0.028) improved significantly in the IG. The STST at 6 months was not significant. Sleep duration and sleep efficiency showed no significant differences between the two groups at any time. Conclusions A comprehensive program by using the Kaia app following PR maintained PA and improved symptoms in patients with COPD at 6 months. The app might be an important accessory tool for enhanced COPD care.Trial registration number DRKS00017275.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Inhalation therapy with nebulized capsaicin in a patient with oropharyngeal dysphagia post stroke. A clinical case report
    (MDPI, 2022) Pekacka-Egli, Anna Maria; Herrmann, Jana; Spielmanns, Marc; Goerg, Arthur; Schulz, Katharina; Zenker, Eveline; Windisch, Wolfram; Kulnik, Stefan Tino [in: Geriatrics]
    Dysphagia and aspiration risk are common sequelae of stroke, leading to increased risk of stroke-associated pneumonia. This is often aggravated by stroke-related impairment of cough, the most immediate mechanical defense mechanism against aspiration. In humans, reflex cough can be repeatedly and safely elicited by inhalation of nebulized capsaicin, a compound contained in chili peppers. Could this cough-eliciting property of capsaicin support the recovery of stroke survivors who present with dysphagia and aspiration risk? We present a clinical case report of a 73-year-old man, admitted to inpatient stroke rehabilitation following a right middle cerebral artery infarct with subsequent dysphagia and hospital-acquired pneumonia. A course of daily inhalation therapy with nebulized capsaicin was initiated, triggering reflex coughs to support secretion clearance and prevent recurrence of pneumonia. Clinical observations in each inhalation therapy session demonstrate good patient response, safety and tolerability of nebulized capsaicin in this mode of application. Repeated Fiberoptic Endoscopic Evaluation of Swallowing (FEES) assessments show concurrent improvement in the patient’s swallowing status. Inhalation therapy with nebulized capsaicin may offer a viable treatment to facilitate coughing and clearing of secretions, and to minimize aspiration and risk of aspiration-related pneumonia post stroke. Further investigation in a randomized controlled trial design is warranted.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    SSP/SSTS – EFP Joint Annual Conference 2021
    (Karger, 2021) Pekacka-Egli, Anna Maria [in: Respiration]
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Natalia Zylberlast-Zand (1883–1942)
    (Springer, 2021) Pekacka-Falkowska, Katarzyna; Pekacka-Egli, Anna Maria [in: Irish Journal of Medical Science]
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Predictive value of cough frequency in addition to aspiration risk for increased risk of pneumonia in dysphagic stroke survivors. A clinical pilot study
    (MDPI, 2021) Pekacka-Egli, Anna Maria; Kazmierski, Radoslaw; Lutz, Dietmar; Kulnik, Stefan Tino; Pekacka-Falkowska, Katarzyna; Maszczyk, Adam; Windisch, Wolfram; Boeselt, Tobias; Spielmanns, Marc [in: Brain Sciences]
    Background: Post-stroke dysphagia leads to increased risk of aspiration and subsequent higher risk of pneumonia. It is important to not only diagnose post-stroke dysphagia early but also to evaluate the protective mechanism that counteracts aspiration, i.e., primarily cough. The aim of this study was to investigate the predictive value of cough frequency in addition to aspiration risk for pneumonia outcome. Methods: This was a single-center prospective observational study. Patients with first-ever strokes underwent clinical swallowing evaluation, fibreoptic endoscopic evaluation of swallowing (FEES), and overnight cough recording using LEOSound® (Löwenstein Medical GmbH & Co. KG, Bad Ems, Germany ). Penetration–Aspiration Scale (PAS) ratings and cough frequency measurements were correlated with incidence of pneumonia at discharge. Results: 11 women (37%) and 19 men (63%), mean age 70.3 years (SD ± 10.6), with ischemic stroke and dysphagia were enrolled. Correlation analysis showed statistically significant relationships between pneumonia and PAS (r = 0.521; p < 0.05), hourly cough frequency (r = 0,441; p < 0.05), and categories of cough severity (r = 0.428 p < 0.05), respectively. Logistic regression showed significant predictive effects of PAS (b = 0.687; p = 0.014) and cough frequency (b = 0.239; p = 0.041) for pneumonia outcome. Conclusion: Cough frequency in addition to aspiration risk was an independent predictor of pneumonia in dysphagic stroke survivors.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Clinical and functional predictors of response to a comprehensive pulmonary rehabilitation in severe post-COVID-19 patients
    (MDPI, 2021) Spielmanns, Marc; Buelow, Melissa Masha; Pekacka-Egli, Anna Maria; Cecon, Mikis; Spielmanns, Sabine; Windisch, Wolfram; Hermann, Matthias [in: Microorganisms]
    Background: Pulmonary rehabilitation (PR) following severe and very severe COVID-19 infection is known to be effective, according to typical assessments. However, not all patients benefit from PR to the same extent. This analysis aimed to identify the impact of different factors on PR outcomes in post-COVID-19 patients. Methods: This prospective observational study included 184 post-COVID-19 patients. The achievement of the predicted reference walking distance (6 min walking distance (6-MWD)) served as a parameter with which to identify responders and non-responders to PR. Several parameters (e.g., Functional Independent Measurement (FIM); pulmonary function testing (Forced Vital Capacity, FVC); 6MWD) were assessed in order to estimate their impact on PR success. Logistic regression models and classification and regression trees were used for multivariate analysis. Results: A total of 94 patients (51%) reached their reference 6MWD by the end of PR. FVC (0.95 (0.93–0.97)), 6MWD at admission (0.99 (0.99–1.00)), and FIM motoric (0.96 (0.93–0.99)) correlated with the risk not reaching the reference distance. The most important variable was the 6MWD at admission. Classification and regression tree identified 6MWD ≥ 130 m at admission and FVC predicted of >83% as the strongest predictor for reaching predicted 6-MWD. Conclusion: Post-COVID-19 patients with lower 6MWD, lower motoric FIM scores and lower FVC at admission have a high risk of not reaching their target values of physical performance despite intensive rehabilitation. As well as identifying them, it is of utmost importance to develop optimal PR concepts for these patients.
    01A - Beitrag in wissenschaftlicher Zeitschrift
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    Publikation
    Reassessment of poststroke dysphagia in rehabilitation facility results in reduction in diet restrictions
    (MDPI, 2021) Pekacka-Egli, Anna Maria; Kazmierski, Radoslaw; Lutz, Dietmar; Pekacka-Falkowska, Katarzyna; Maszczyk, Adam; Windisch, Wolfram; Spielmanns, Marc [in: Journal of Clinical Medicine]
    Background: Dysphagia assessment in postacute stroke patients can decrease the incidence of complications like malnutrition, dehydration, and aspiration pneumonia. It also helps to avoid unnecessary diet restrictions. The aim of this study is to verify if regular reassessment of dysphagia would change the diet management of postacute stroke patients in rehabilitation settings. Methods: This single-center retrospective study included 63 patients referred to an inpatient neurological rehabilitation center between 2018–2019. A standardized clinical swallowing evaluation and Fiberoptic Endoscopic Evaluation of Swallowing (FEES) were performed. Diet level according to Functional Oral Intake Scale (FOIS) was evaluated. As the primary endpoint, the FOIS values based on diagnostic procedures were assessed at hospital discharge, rehabilitation admission, and after FEES. Results: 19 women (30%) and 44 men (70%), with a mean age of 75 y (SD ± 10.08), were enrolled. The intergroup ANOVA revealed significant differences (p < 0.001) between dietary prescriptions in an acute care setting and following clinical and endoscopic reassessment in the rehabilitation center. Diet recommendations changed in 41 of 63 (65%) enrolled patients (p < 0.001). Conclusion: Instrumental diagnostic by FEES during the early convalescence period of stroke patients leads to clinically relevant changes to diet restrictions and lower rates of pneumonia. Our findings underline the need for regular and qualitative dysphagia diagnostics in stroke patients participating in neurological rehabilitation.
    01A - Beitrag in wissenschaftlicher Zeitschrift