Pieles, Uwe

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Pieles, Uwe

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Amino acid composition of nanofibrillar self-assembling peptide hydrogels affects responses of periodontal tissue cells in vitro

2018-10, Koch, Franziska, Wolff, Anne, Mathes, Stephanie, Pieles, Uwe, Saxer, Sina, Kreikemeyer, Bernd, Peters, Kirsten

The regeneration of tissue defects at the interface between soft and hard tissue, eg, in the periodontium, poses a challenge due to the divergent tissue requirements. A class of biomaterials that may support the regeneration at the soft-to-hard tissue interface are self-assembling peptides (SAPs), as their physicochemical and mechanical properties can be rationally designed to meet tissue requirements.