2022, Löffler, Emanuel, Schneider, Bettina, Goerre, Andreas, Asprion, Petra, Filipe, Joaquim, Smialek, Michal, Brodsky, Alexander, Hammoudi, Slimane

2019, Schneider, Bettina, Asprion, Petra, Grimberg, Frank, Filipe, Joaquim, Smialek, Michal, Brodsky, Alexander, Hammoudi, Slimane

This study indicates the significance of a human-centered perspective in the analysis and interpretation of Real World Data. As an exemplary use-case, the construct of perceived ‘Health-related Quality of Life’ is chosen to show, firstly, the significance of Real World Data and, secondly, the associated ‘Real World Evidence’. We settled on an iterative methodology and used hermeneutics for a detailed literature analysis to outline the relevance and the need for a forward-thinking approach to deal with Real World Evidence in the life science and health care industry. The novelty of the study is its focus on a human-centered artificial intelligence, which can be achieved by using ‘System Dynamics’ modelling techniques. The outcome – a human-centered ‘Indicator Set’ can be combined with results from data-driven, AI-based analytics. With this multidimensional approach, human intelligence and artificial intelligence can be intertwined towards an enriched Real World Evidence. The developed approach considers three perspectives – the elementary, the algorithmic and – as novelty – the human-centered evidence. As conclusion, we claim that Real World Data are more valuable and applicable to achieve patient-centricity and personalization if the human-centered perspective is considered ‘by design’.

2019, Siddhanti, Pragati, Asprion, Petra, Schneider, Bettina, Filipe, Joaquim, Smialek, Michal, Brodsky, Alexander, Hammoudi, Slimane

The Internet of Things (IoT) is being increasingly adopted by businesses to improve operations, processes, and products. While it opens endless opportunities, it also presents tremendous challenges especially in the area of cyber risks and related security controls. With billions of interconnected devices worldwide, how do we ensure that they are sufficiently secure and resilient? As a reasonable solution, ‘Cybersecurity by Design’ seems a promising approach. In this research, ‘Smart Homes’ - as IoT containing products – are selected as unit of analysis because they are exposed to numerous cyber threats with corresponding adverse consequences for the life, safety and health of residents. By aiming to secure Smart Home Environments (SHEs) from cyber threats, we adopted ‘design science’ as methodology and developed a holistic approach, highlighting ‘good practices’, which can be applied in every phase of the SHEs product lifecycle. In addition to these good practices, a ‘Cyber Security Maturity Assessment’ tool for SHEs has been developed. Both artefacts have already been validated and incrementally improved, and are now awaiting their future application and further enhancements.