Interferometric label-free biomolecular detection system
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Author (Corporation)
Publication date
2006
Type of student thesis
Course of study
Type
01A - Journal article
Editors
Editor (Corporation)
Supervisor
Parent work
Journal of Optics A: Pure and Applied Optics
Special issue
DOI of the original publication
Link
Related research data
Series
Series number
Volume
8
Issue / Number
7
Pages / Duration
360-364
Patent number
Publisher / Publishing institution
IOP Publishing
Place of publication / Event location
Edition
Version
Programming language
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Practice partner / Client
Abstract
This work presents a simple evanescent wave sensing system based on an interferometric approach, suitable to meet the requirements of label-free sensor systems for detecting biomolecular interactions. It represents a basic concept towards label-free detection systems in various applications.
The basic objectives of transducers for evanescent wave sensing are discussed. An optical detection system based on a interferometric approach using Young's double slit configuration is discussed, set-up and characterized.
With refractometric measurements of various sucrose dilutions, the performance of the pure optical set-up is evaluated.
Keywords
Interferometer, Evanescence wave sensing, Integrated optics, Biosensor
Subject (DDC)
Event
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ISBN
ISSN
1464-4258
1741-3567
1741-3567
Language
English
Created during FHNW affiliation
No
Strategic action fields FHNW
Publication status
Published
Review
peer-reviewed
Open access category
Closed
License
Citation
Hradetzky, D., Mueller, C., & Reinecke, H. (2006). Interferometric label-free biomolecular detection system. Journal of Optics A: Pure and Applied Optics, 8(7), 360–364. https://doi.org/10.1088/1464-4258/8/7/s11