Editorial: The RNA revolution and cancer
Author (Corporation)
Publication date
20.05.2024
Typ of student thesis
Course of study
Collections
Type
01A - Journal article
Editors
Editor (Corporation)
Supervisor
Parent work
Frontiers in Endocrinology
Special issue
DOI of the original publication
Link
Series
Series number
Volume
15
Issue / Number
Pages / Duration
Patent number
Publisher / Publishing institution
Frontiers Research Foundation
Place of publication / Event location
Edition
Version
Programming language
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Practice partner / Client
Abstract
RNA biology has revolutionized cancer understanding and treatment, especially in endocrine-related malignancies. This editorial highlights RNA's crucial role in cancer progression, emphasizing its influence on tumor heterogeneity and behavior. Processes like alternative splicing and noncoding RNA regulation shape cancer biology, with microRNAs, long noncoding RNAs, and circular RNAs orchestrating gene expression dynamics. Aberrant RNA signatures hold promise as diagnostic and prognostic biomarkers in endocrine-related cancers. Recent findings, such as aberrant PI3Kδ splice isoforms and epithelial-mesenchymal transition-related lncRNA signatures, unveil potential therapeutic targets for personalized treatments. Insights into m6A-associated lncRNA prognostic models and the function of lncRNA LINC00659 in gastric cancer represents ongoing research in this field. As understanding of RNA's role in cancer expands, personalized therapies offer transformative potential in managing endocrine-related malignancies. This signifies a significant stride towards precision oncology, fostering innovation for more effective cancer care.
Keywords
Subject (DDC)
500 - Naturwissenschaften und Mathematik
Event
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Exhibition end date
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ISBN
ISSN
1664-2392
Language
English
Created during FHNW affiliation
Yes
Strategic action fields FHNW
Publication status
Published
Review
Peer review of the complete publication
Open access category
Gold
License
Citation
DLAMINI, Zodwa, Michael R. LADOMERY und Abdullah KAHRAMAN, 2024. Editorial: The RNA revolution and cancer. Frontiers in Endocrinology. 20 Mai 2024. Bd. 15. DOI 10.3389/fendo.2024.1422599. Verfügbar unter: https://doi.org/10.26041/fhnw-11810