A new model of implant-related osteomyelitis in the metaphysis of rat tibiae
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Authors
Harrasser, Norbert
Gorkotte, Johannes
Obermeier, Andreas
Feihl, Susanne
Straub, Melanie
Slotta-Huspenina, Julia
von Eisenhart-Rothe, Ruediger
Moser, Walter
Gruner, Philipp
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Publication date
08.04.2016
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01A - Journal article
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BMC Musculoskeletal Disorders
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BioMed Central
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Abstract
Animal models serve as an important tool to understand peri-implant infection. Most of the models use high bacterial loads (>104 colony forming units, CFU) to provide high infection rates. Therefore these animals evolve rather similarly, making comparison between groups and statistical analysis possible. On the other hand, to mimic clinical constellation of surgery-related infections the use of low amounts of bacteria would be more advantageous.
Keywords
Rat, Screw, Metaphysis, Staphylococcus aureus, Implant-associated infections
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1471-2474
Language
English
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Yes
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Published
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HARRASSER, Norbert, Johannes GORKOTTE, Andreas OBERMEIER, Susanne FEIHL, Melanie STRAUB, Julia SLOTTA-HUSPENINA, Ruediger VON EISENHART-ROTHE, Walter MOSER, Philipp GRUNER, Michael DE WILD, Hans GOLLWITZER und Rainer BURGKART, 2016. A new model of implant-related osteomyelitis in the metaphysis of rat tibiae. BMC Musculoskeletal Disorders. 8 April 2016. DOI 10.1186/s12891-016-1005-z. Verfügbar unter: http://hdl.handle.net/11654/23576