In-situ recovery of carboxylic acids from fermentation broths through membrane supported reactive extraction using membrane modules with improved stability

dc.accessRightsAnonymous*
dc.audienceScienceen_US
dc.contributor.authorGössi, Angelo
dc.contributor.authorBurgener, Florian
dc.contributor.authorKohler, David
dc.contributor.authorUrso, Alessandro
dc.contributor.authorKolvenbach, Boris
dc.contributor.authorRiedl, Wolfgang
dc.date.accessioned2020-03-03T08:50:57Z
dc.date.available2020-03-03T08:50:57Z
dc.date.issued2020-06-15
dc.description.abstractMembrane supported reactive extraction (MSE) coupled to back-extraction (MSBE) using a new type of Teflon (PTFE) capillary membrane contactor was studied for the in-situ removal of carboxylic acids from aqueous streams, e.g. fermentation broths. The use of microporous membranes as extraction interface helps avoiding emulsification problems, allows the use of extreme phase ratios, and protects microorganisms, as they are less affected by solvent toxicity during in-situ extractions. The use of PTFE capillary membranes is suitable for long-term use due its high chemical and thermal stability. A simple toxicity screening identified n-decanol with tri n-octyl amine (TOA) as a suitable solvent. MSE experiments were performed using membrane contactors (0.005 m2 to 0.15 m2), working with solvent to feed phase ratios down to 1:40 (mass based). The in-situ removal of lactic acid out of fermentation broths using lactobacillus plantarum led to a glucose conversion rate of 80 mol%. Additionally, a concentration factor up to 7.8 could be shown during back-extraction.en_US
dc.description.urihttps://www.sciencedirect.com/science/article/pii/S1383586619344478#!en_US
dc.identifier.doi10.1016/j.seppur.2020.116694
dc.identifier.issn1873-3794
dc.identifier.issn1383-5866
dc.identifier.urihttps://irf.fhnw.ch/handle/11654/30652
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofSeparation and Purification Technologyen_US
dc.subjectReactive extractionen_US
dc.subjectProcess intensificationen_US
dc.subjectProduct recoveryen_US
dc.subjectCarboxylic acidsen_US
dc.subjectMembrane extraction processen_US
dc.titleIn-situ recovery of carboxylic acids from fermentation broths through membrane supported reactive extraction using membrane modules with improved stabilityen_US
dc.type01A - Beitrag in wissenschaftlicher Zeitschrift
dc.volume241en_US
dspace.entity.typePublication
fhnw.InventedHereYesen_US
fhnw.IsStudentsWorknoen_US
fhnw.PublishedSwitzerlandYesen_US
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publicationen_US
fhnw.affiliation.hochschuleHochschule für Life Sciencesde_CH
fhnw.affiliation.institutInstitut für Chemie und Bioanalytikde_CH
fhnw.publicationOnlineJaen_US
fhnw.publicationStatePublisheden_US
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relation.isAuthorOfPublication.latestForDiscovery309981e9-45aa-4243-a3ac-b8cbcbc25e02
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