Recommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility

dc.contributor.authorPamies, David
dc.contributor.authorEkert, Jason
dc.contributor.authorZurich, Marie-Gabrielle
dc.contributor.authorFrey, Olivier
dc.contributor.authorWerner, Sophie
dc.contributor.authorPiergiovanni, Monica
dc.contributor.authorFreedman, Benjamin S.
dc.contributor.authorKeong Teo, Adrian Kee
dc.contributor.authorErfurth, Hendrik
dc.contributor.authorReyes, Darwin R.
dc.contributor.authorLoskill, Peter
dc.contributor.authorCandarlioglu, Pelin
dc.contributor.authorSuter-Dick, Laura
dc.contributor.authorWang, Shan
dc.contributor.authorHartung, Thomas
dc.contributor.authorCoecke, Sandra
dc.contributor.authorStacey, Glyn N.
dc.contributor.authorWagegg, Beren Atac
dc.contributor.authorDehne, Eva-Maria
dc.contributor.authorPistollato, Francesca
dc.contributor.authorLeist, Marcel
dc.date.accessioned2025-03-10T14:40:26Z
dc.date.issued2024-05
dc.description.abstractCell culture technology has evolved, moving from single-cell and monolayer methods to 3D models like reaggregates, spheroids, and organoids, improved with bioengineering like microfabrication and bioprinting. These advancements, termed microphysiological systems (MPSs), closely replicate tissue environments and human physiology, enhancing research and biomedical uses. However, MPS complexity introduces standardization challenges, impacting reproducibility and trust. We offer guidelines for quality management and control criteria specific to MPSs, facilitating reliable outcomes without stifling innovation. Our fit-for-purpose recommendations provide actionable advice for achieving consistent MPS performance.
dc.identifier.doi10.1016/j.stemcr.2024.03.009
dc.identifier.issn2213-6711
dc.identifier.urihttps://irf.fhnw.ch/handle/11654/49951
dc.identifier.urihttps://doi.org/10.26041/fhnw-11822
dc.issue5
dc.language.isoen
dc.publisherCell Press
dc.relation.ispartofStem Cell Reports
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.ddc500 - Naturwissenschaften und Mathematik
dc.titleRecommendations on fit-for-purpose criteria to establish quality management for microphysiological systems and for monitoring their reproducibility
dc.type01A - Beitrag in wissenschaftlicher Zeitschrift
dc.volume19
dspace.entity.typePublication
fhnw.InventedHereYes
fhnw.ReviewTypeAnonymous ex ante peer review of a complete publication
fhnw.affiliation.hochschuleHochschule für Life Sciences FHNWde_CH
fhnw.affiliation.institutInstitut für Chemie und Bioanalytikde_CH
fhnw.openAccessCategoryGold
fhnw.pagination604-617
fhnw.publicationStatePublished
relation.isAuthorOfPublicationf29d0ce1-5495-463f-9842-a1c5212e45af
relation.isAuthorOfPublication37292405-e311-4093-a2e7-9a72a2511114
relation.isAuthorOfPublication.latestForDiscoveryf29d0ce1-5495-463f-9842-a1c5212e45af
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