Quantitative assessment of point-of-care 3D-printed patient-specific polyetheretherketone (PEEK) cranial implants

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Authors
Sharma, Neha
Aghlmandi, Soheila
Zeilhofer, Hans-Florian
Thieringer, Florian
Honigmann, Philipp
Author (Corporation)
Publication date
07.08.2021
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01A - Journal article
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Parent work
International Journal of Molecular Sciences
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Volume
22
Issue / Number
16
Pages / Duration
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Publisher / Publishing institution
MDPI
Place of publication / Event location
Basel
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Abstract
Recent advancements in medical imaging, virtual surgical planning (VSP), and three-dimensional (3D) printing have potentially changed how today’s craniomaxillofacial surgeons use patient information for customized treatments. Over the years, polyetheretherketone (PEEK) has emerged as the biomaterial of choice to reconstruct craniofacial defects. With advancements in additive manufacturing (AM) systems, prospects for the point-of-care (POC) 3D printing of PEEK patient-specific implants (PSIs) have emerged. Consequently, investigating the clinical reliability of POC-manufactured PEEK implants has become a necessary endeavor. Therefore, this paper aims to provide a quantitative assessment of POC-manufactured, 3D-printed PEEK PSIs for cranial reconstruction through characterization of the geometrical, morphological, and biomechanical aspects of the in-hospital 3D-printed PEEK cranial implants. The study results revealed that the printed customized cranial implants had high dimensional accuracy and repeatability, displaying clinically acceptable morphologic similarity concerning fit and contours continuity. From a biomechanical standpoint, it was noticed that the tested implants had variable peak load values with discrete fracture patterns and failed at a mean (SD) peak load of 798.38 ± 211.45 N. In conclusion, the results of this preclinical study are in line with cranial implant expectations; however, specific attributes have scope for further improvements.
Keywords
Alloplastic implant, Biocompatible material, Computer-assisted, Cranioplasty, Fused filament fabrication, Reconstructive surgery, Patient-specific modeling, Printing, Polymer, Three-dimensional
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ISSN
1661-6596
1422-0067
Language
English
Created during FHNW affiliation
Yes
Publication status
Published
Review
Peer review of the complete publication
Open access category
Gold
License
'http://creativecommons.org/licenses/by/3.0/us/'
Citation
SEILER, Daniel, Federico DALCANALE, Neha SHARMA, Soheila AGHLMANDI, Hans-Florian ZEILHOFER, Florian THIERINGER und Philipp HONIGMANN, 2021. Quantitative assessment of point-of-care 3D-printed patient-specific polyetheretherketone (PEEK) cranial implants. International Journal of Molecular Sciences. 7 August 2021. Bd. 22, Nr. 16. DOI 10.3390/ijms22168521. Verfügbar unter: https://doi.org/10.26041/fhnw-4119