An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations
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Authors
Dussy, Franz
Hangartner, Sarah
Hamberg, Cornelia
Berchtold, Christoph
Scherer, Ulrich
Wyler, David
Briellmann, Thomas
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Publication date
2016
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01A - Journal article
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Journal of Analytical Toxicology
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Volume
40
Issue / Number
9
Pages / Duration
761-766
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Oxford University Press
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Abstract
A 24-year-old man known to consume illegal drugs was found dead in his apartment. A reclosable plastic zipper bag containing several hundred milligrams of a brown powder was found close to the dead body and the first assumption of the investigators was death due to heroin intoxication. Therefore, a legal autopsy was ordered. The following toxicological analysis revealed ocfentanil in urine and in the brown powder. Four different approaches for the determination of the ocfentanil concentrations in peripheral whole blood are described. Enrichment of ocfentanil from the powder was realized. With this reference, it was possible to determine the ocfentanil concentration in the seized powder to be 0.91%. Concentrations of ocfentanil were also determined in the sampled body fluids using the standard addition procedure. In peripheral blood 9.1 µg/L, in heart blood 27.9 µg/L and in urine 480 µg/L were measured. In addition, the antidepressant citalopram, the neuroleptic quetiapine and cannabinoids were found in urine and subsequently quantified in peripheral blood.
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1945-2403
0146-4760
0146-4760
Language
English
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Yes
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Publication status
Preprint
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Citation
DUSSY, Franz, Sarah HANGARTNER, Cornelia HAMBERG, Christoph BERCHTOLD, Ulrich SCHERER, Götz SCHLOTTERBECK, David WYLER und Thomas BRIELLMANN, 2016. An Acute Ocfentanil Fatality: A Case Report with Postmortem Concentrations. Journal of Analytical Toxicology. 2016. Bd. 40, Nr. 9, S. 761–766. DOI 10.1093/jat/bkw096. Verfügbar unter: http://hdl.handle.net/11654/23644