Intraoperative acceleration measurements to quantify tremor during deep brain stimulation surgery
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Autor:innen
Coste, Jérôme
Lemaire, Jean-Jaques
Taub, Ethan
Schüpbach, W.M. Michael
Pollo, Claudio
Guzman, Raphael
Autor:in (Körperschaft)
Publikationsdatum
2016
Typ der Arbeit
Studiengang
Typ
01A - Beitrag in wissenschaftlicher Zeitschrift
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Übergeordnetes Werk
Medical & Biological Engineering & Computing
Themenheft
DOI der Originalpublikation
Reihe / Serie
Reihennummer
Jahrgang / Band
Ausgabe / Nummer
Seiten / Dauer
1-14
Patentnummer
Verlag / Herausgebende Institution
Springer
Verlagsort / Veranstaltungsort
Auflage
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
Deep brain stimulation (DBS) surgery is extensively used in the treatment of movement disorders. Nevertheless, methods to evaluate the clinical response during intraoperative stimulation tests to identify the optimal position for the implantation of the chronic DBS lead remain subjective. In this paper, we describe a new, versatile method for quantitative intraoperative evaluation of improvement in tremor with an acceleration sensor that is mounted on the patient’s wrist during surgery. At each anatomical test position, the improvement in tremor compared to the initial tremor is estimated on the basis of extracted outcome measures. This method was tested on 15 tremor patients undergoing DBS surgery in two centers. Data from 359 stimulation tests were acquired. Our results suggest that accelerometric evaluation detects tremor changes more sensitively than subjective visual ratings. The effective stimulation current amplitudes identified from the quantitative data (1.1 ± 0.8 mA) are lower than those identified by visual evaluation (1.7 ± 0.8 mA) for similar improvement in tremor. Additionally, if these data had been used to choose the chronic implant position of the DBS lead, 15 of the 26 choices would have been different. These results show that our method of accelerometric evaluation can potentially improve DBS targeting.
Schlagwörter
Deep brain stimulation, Intraoperative monitoring, Essential tremor, Acceleration, Tremor, Parkinson’s disease
Fachgebiet (DDC)
Veranstaltung
Startdatum der Ausstellung
Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
ISSN
0140-0118
1741-0444
1741-0444
Sprache
Englisch
Während FHNW Zugehörigkeit erstellt
Ja
Publikationsstatus
Veröffentlicht
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Lizenz
Zitation
SHAH, Ashesh, Jérôme COSTE, Jean-Jaques LEMAIRE, Ethan TAUB, W.M. Michael SCHÜPBACH, Claudio POLLO, Erik SCHKOMMODAU, Raphael GUZMAN und Simone HEMM-ODE, 2016. Intraoperative acceleration measurements to quantify tremor during deep brain stimulation surgery. Medical & Biological Engineering & Computing. 2016. S. 1–14. DOI 10.1007/s11517-016-1559-9. Verfügbar unter: http://hdl.handle.net/11654/23575