Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide
dc.accessRights | Anonymous | |
dc.audience | Science | |
dc.contributor.author | Kind, Lucy | |
dc.contributor.author | Stevanovic, Sabrina | |
dc.contributor.author | Wuttig, Sina | |
dc.contributor.author | Wimberger, Sandra | |
dc.contributor.author | Hofer, Joëlle | |
dc.contributor.author | Müller, Bert | |
dc.contributor.author | Pieles, Uwe | |
dc.date.accessioned | 2017-06-22T05:47:03Z | |
dc.date.available | 2017-06-22T05:47:03Z | |
dc.date.issued | 2017-03-27 | |
dc.description.abstract | Self-assembling β-sheet forming peptide P11-4 has shown potential in the treatment and prevention of dental caries by supporting tissue regeneration. It has previously been shown that application of monomeric P11-4 solution to early carious lesions can increase net mineral gain by forming de novo hydroxyapatite crystals. The hypothesis for the mode of action was that monomeric self-assembling peptide P11-4 diffuses into the subsurface lesion body and assembles therein into higher order fibrils, facilitating mineralization of the subsurface volume by mimicking the natural biomineralization of the tooth enamel. | |
dc.identifier.doi | https://doi.org/10.1177/0022034517698419 | |
dc.identifier.issn | 0022-0345 | |
dc.identifier.issn | 1544-0591 | |
dc.identifier.uri | http://hdl.handle.net/11654/25070 | |
dc.identifier.uri | https://doi.org/10.26041/fhnw-1104 | |
dc.language.iso | en | en_US |
dc.publisher | SAGE | en_US |
dc.relation.ispartof | Journal of Dental Research | en_US |
dc.subject | enamel biomineralization/formation | |
dc.subject | micro–computed tomography | |
dc.subject | regeneration | |
dc.subject | scanning electron microscopy (SEM) | |
dc.subject | dentistry | |
dc.title | Biomimetic Remineralization of Carious Lesions by Self-Assembling Peptide | |
dc.type | 01A - Beitrag in wissenschaftlicher Zeitschrift | |
dspace.entity.type | Publication | |
fhnw.InventedHere | Yes | |
fhnw.IsStudentsWork | no | |
fhnw.PublishedSwitzerland | No | |
fhnw.ReviewType | Lectoring (ex ante) | |
fhnw.affiliation.hochschule | Hochschule für Life Sciences FHNW | de_CH |
fhnw.affiliation.institut | Institut für Chemie und Bioanalytik | de_CH |
fhnw.pagination | 1-8 | |
fhnw.publicationOnline | Ja | |
fhnw.publicationState | Published | |
relation.isAuthorOfPublication | 62f9c87a-a655-482a-a9b4-56720f9d607d | |
relation.isAuthorOfPublication.latestForDiscovery | 62f9c87a-a655-482a-a9b4-56720f9d607d |
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