Investigation of structural resorption behavior of biphasic bioceramics with help of gravimetry, μCT, SEM, and XRD
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Autor:innen
Autor:in (Körperschaft)
Publikationsdatum
07.05.2015
Typ der Arbeit
Studiengang
Typ
01A - Beitrag in wissenschaftlicher Zeitschrift
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Übergeordnetes Werk
Journal of Biomedical Materials Research. Part B: Applied Biomaterials
Themenheft
DOI der Originalpublikation
Link
Reihe / Serie
Reihennummer
Jahrgang / Band
Ausgabe / Nummer
Seiten / Dauer
1-8
Patentnummer
Verlag / Herausgebende Institution
Verlagsort / Veranstaltungsort
Auflage
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
Resorbable bone substitute materials are widely used for bone augmentation after tumor resection, parallel to implant placement, or in critical size bone defects. In this study, the structural dissolution of a biphasic calcium phosphate bone substitute material with a hydroxyapatite (HA)/tricalcium phosphate (ß-TCP) ratio of 60/40 was investigated by repeatedly placing porous blocks in EDTA solution at 37°C. At several time points, the blocks were investigated by SEM, µCT, and gravimetry. It was found that always complete 2–3 µm sized grains were removed from the structure and that the ß-TCP is dissolved more rapidly. This selective dissolution of the ß-TCP grains was confirmed by XRD measurements. The blocks were eroded from the outside toward the center. The structure remained mechanically stable because the central part showed a delayed degradation and because the slower dissolving HA grains preserved the integrity of the structure.
Schlagwörter
bioceramic, hydroxylapatite, ß-TCP, selective resorption, µCT/SEM/XRD
Fachgebiet (DDC)
Veranstaltung
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Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
ISSN
Sprache
Englisch
Während FHNW Zugehörigkeit erstellt
Ja
Zukunftsfelder FHNW
Publikationsstatus
Veröffentlicht
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Lizenz
Zitation
de Wild, M., Molenberg, A., Amacher, F., & Chris, B. (2015). Investigation of structural resorption behavior of biphasic bioceramics with help of gravimetry, μCT, SEM, and XRD. Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 1–8. https://doi.org/10.1002/jbm.b.33419.