Toothpastes with enzymes support gum health and reduce plaque formation
dc.accessRights | Anonymous | * |
dc.contributor.author | Paque, Pune | |
dc.contributor.author | Schmidlin, Patrick | |
dc.contributor.author | Wiedemeier, Daniel | |
dc.contributor.author | Wegehaupt, Florian | |
dc.contributor.author | Burrer, Phoebe | |
dc.contributor.author | Körner, Philipp | |
dc.contributor.author | Deari, Shengjile | |
dc.contributor.author | Sciotti, Michel | |
dc.contributor.author | Attin, Thomas | |
dc.date.accessioned | 2022-03-14T06:50:51Z | |
dc.date.available | 2022-03-14T06:50:51Z | |
dc.date.issued | 2021-01-19 | |
dc.description.abstract | Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-containing toothpastes with glucose oxidase and D-glucose with (C+) and without Citrox (C−) Citrox) were investigated in a clinical crossover trial (two slurries: sodium lauryl sulfate-containing (SLS), a toothpaste without SLS (reference), and water). Subjects (n = 20) abstained from toothbrushing for four days and rinsed with a toothpaste slurry. Bleeding on probing (BOP) and plaque indices (PI) were measured. A mixed linear model was used to statistically compare the slurries with respect to BOP and PI change. The in vitro bacterial growth-inhibiting evaluation showed the best results for SLS, followed by C+ and C−. The change in BOP and PI exhibited statistically significant differences to water rinsing (BOP; PI changes in % points (difference of the baseline and post-rinse values: water = 8.8%; 90.0%; C+ = −1.4%; 80.4%; SLS = 1.5%; 72.1%; reference = 0.8%; 77.5%; C− = −1.8%; 75.1%). All slurries exhibited anti-gingivitis and anti-plaque effects, resulting in a prophylactic benefit for limited-access regions during brushing. | en_US |
dc.identifier.doi | 10.3390/ijerph18020835 | |
dc.identifier.issn | 1661-7827 | |
dc.identifier.issn | 1660-4601 | |
dc.identifier.uri | https://irf.fhnw.ch/handle/11654/33344 | |
dc.identifier.uri | https://doi.org/10.26041/fhnw-4127 | |
dc.issue | 835 | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | MDPI | en_US |
dc.relation.ispartof | International Journal of Environmental Research and Public Health | en_US |
dc.rights | Attribution 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | en_US |
dc.spatial | Basel | en_US |
dc.subject | Gingiva | en_US |
dc.subject | Toothbrushing | en_US |
dc.subject | Dentifrice | en_US |
dc.subject | Prophylaxis | en_US |
dc.subject | Prevention | en_US |
dc.subject | Bacteria | en_US |
dc.subject | Gingivitis | en_US |
dc.subject | Low responder | en_US |
dc.subject | High responder | en_US |
dc.title | Toothpastes with enzymes support gum health and reduce plaque formation | en_US |
dc.type | 01A - Beitrag in wissenschaftlicher Zeitschrift | |
dc.volume | 18 | en_US |
dspace.entity.type | Publication | |
fhnw.InventedHere | Yes | en_US |
fhnw.IsStudentsWork | no | en_US |
fhnw.ReviewType | Anonymous ex ante peer review of a complete publication | en_US |
fhnw.affiliation.hochschule | Hochschule für Life Sciences FHNW | de_CH |
fhnw.affiliation.institut | Institut für Chemie und Bioanalytik | de_CH |
fhnw.openAccessCategory | Gold | en_US |
fhnw.pagination | 1-14 | en_US |
fhnw.publicationState | Published | en_US |
relation.isAuthorOfPublication | 74cb5247-116c-4ae5-b438-d4315099720d | |
relation.isAuthorOfPublication.latestForDiscovery | 74cb5247-116c-4ae5-b438-d4315099720d |
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