Label free detection of biomolecular interactions
dc.contributor.author | Hradetzky, David | |
dc.contributor.author | Müller, Claas | |
dc.contributor.author | Reinecke, Holger | |
dc.date.accessioned | 2024-08-13T07:42:40Z | |
dc.date.available | 2024-08-13T07:42:40Z | |
dc.date.issued | 2005 | |
dc.description.abstract | This work presents a simple evanescent wave sensing system based on an interferometric approach suitable to meet the demands on label free sensor systems for the detection of biomolecular interactions especially. It is representing a basic concept towards high throughput application. The system performance and reproducibility was evaluated with refractometric measurements of sucrose dilutions. A mean resolution of the effective refractive index of 3sigma(Deltamacrnmacr eff )=0.9middot10 -6 without averaging and a reproducibility below sigma r =0.1middot10 -6 were achieved. The suitability for the detection of biomolecular interactions was validated with the detection of a DNA hybridization | |
dc.event | IEEE/LEOS International Conference on Optical MEMS and Their Applications Conference | |
dc.event.end | 2005-08-04 | |
dc.event.start | 2005-08-01 | |
dc.identifier.doi | 10.1109/omems.2005.1540087 | |
dc.identifier.isbn | 0-7803-9278-7 | |
dc.identifier.isbn | 2160-5033 | |
dc.identifier.isbn | 2160-5041 | |
dc.identifier.uri | https://irf.fhnw.ch/handle/11654/46769 | |
dc.language.iso | en | |
dc.publisher | IEEE | |
dc.relation.ispartof | IEEE/LEOS International Conference on Optical MEMS and Their Applications Conference, 2005. | |
dc.spatial | Oulu | |
dc.subject.ddc | 600 - Technik, Medizin, angewandte Wissenschaften | |
dc.title | Label free detection of biomolecular interactions | |
dc.type | 04B - Beitrag Konferenzschrift | |
dspace.entity.type | Publication | |
fhnw.InventedHere | No | |
fhnw.ReviewType | Anonymous ex ante peer review of a complete publication | |
fhnw.affiliation.hochschule | Hochschule für Life Sciences FHNW | de_CH |
fhnw.affiliation.institut | Institut für Medizintechnik und Medizininformatik | de_CH |
fhnw.openAccessCategory | Closed | |
fhnw.pagination | 81-82 | |
fhnw.publicationState | Published | |
relation.isAuthorOfPublication | c9dfc5bf-b9cd-4a1b-b606-eee6c639fd56 | |
relation.isAuthorOfPublication.latestForDiscovery | c9dfc5bf-b9cd-4a1b-b606-eee6c639fd56 |
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