How technical innovations may help to prevent drug shortages in switzerland

Type
01A - Journal article
Editors
Editor (Corporation)
Supervisor
Parent work
Chimia
Special issue
DOI of the original publication
Link
Series
Series number
Volume
77
Issue / Number
9
Pages / Duration
616-619
Patent number
Publisher / Publishing institution
Schweizerische Chemische Gesellschaft
Place of publication / Event location
Edition
Version
Programming language
Assignee
Practice partner / Client
Abstract
In this work, we investigated the technical feasibility of 'on-demand' production of selected drugs to cover their demand for a time window of 90 days. We focused on two sub-processes 'automated chemical synthesis' and 'formulation in micropellets'  to enable personalized dosing. The production of drugs 'on-demand' is challenging, important, but also attractive. Switzerland could thus gain access to an additional instrument for increasing resilience for supply-critical drugs. The biggest challenge in the case study presented here is the scalability of automated chemical synthesis and the application range of micropellet formulations.
Keywords
Automation of chemical synthesis, Micropellet formulation, On-demand production, Personalized healthcare
Project
Event
Exhibition start date
Exhibition end date
Conference start date
Conference end date
Date of the last check
ISBN
ISSN
2673-2424
0009-4293
Language
English
Created during FHNW affiliation
Yes
Strategic action fields FHNW
Publication status
Published
Review
Peer review of the complete publication
Open access category
Diamond
License
'https://creativecommons.org/licenses/by/4.0/'
Citation
Gygax, D., Eigenmann, K., Suter, C., Hürzeler Müller, M., Mahmoud, A., Mosbacher, J., & Pöllinger, N. (2023). How technical innovations may help to prevent drug shortages in switzerland. Chimia, 77(9), 616–619. https://doi.org/10.2533/chimia.2023.616