Immobilization of an artificial imine reductase within silica nanoparticles improves its performance
| dc.accessRights | Anonymous | |
| dc.audience | Science | |
| dc.contributor.author | Hestericová, Martina | |
| dc.contributor.author | Correro, Maria Rita | |
| dc.contributor.author | Lenz, Markus | |
| dc.contributor.author | Corvini, Philippe | |
| dc.contributor.author | Shahgaldian, Patrick | |
| dc.contributor.author | Ward, Thomas R. | |
| dc.date.accessioned | 2016-10-21T10:17:33Z | |
| dc.date.available | 2016-10-21T10:17:33Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Silica nanoparticles equipped with an artificial imine reductase (biotinylated iridium complex conjugated with streptavidin) display marked redn. activity toward cyclic imines and NAD. The method, based on immobilization and protection of streptavidin on silica nanoparticles, shields the biotinylated metal cofactor against deactivation yielding >46,000 turnovers in pure samples and 4000 turnovers in crude cellular exts. | |
| dc.identifier.doi | 10.1039/c6cc04604e | |
| dc.identifier.issn | 1359-7345 | |
| dc.identifier.issn | 1364-548X | |
| dc.identifier.uri | http://hdl.handle.net/11654/23403 | |
| dc.issue | 60 | |
| dc.language.iso | en | |
| dc.publisher | Royal Society of Chemistry | en_US |
| dc.relation.ispartof | Chemical Communications | en_US |
| dc.subject | Enzymes | |
| dc.title | Immobilization of an artificial imine reductase within silica nanoparticles improves its performance | |
| dc.type | 01A - Beitrag in wissenschaftlicher Zeitschrift | |
| dc.volume | 52 | |
| dspace.entity.type | Publication | |
| fhnw.InventedHere | Yes | |
| fhnw.IsStudentsWork | no | |
| fhnw.PublishedSwitzerland | No | |
| fhnw.ReviewType | Anonymous ex ante peer review of a complete publication | |
| fhnw.affiliation.hochschule | Hochschule für Life Sciences FHNW | de_CH |
| fhnw.affiliation.institut | Institut für Ecopreneurship | de_CH |
| fhnw.pagination | 9462-9465 | |
| fhnw.publicationOnline | Ja | |
| fhnw.publicationState | Published | |
| relation.isAuthorOfPublication | 63a7a9c3-94fa-4df9-96d8-c81d902912ab | |
| relation.isAuthorOfPublication | c7b0a617-ef2c-48b2-919e-18d2c62cc929 | |
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| relation.isAuthorOfPublication | 8884cd16-817b-4fba-a564-50a45970baa2 | |
| relation.isAuthorOfPublication.latestForDiscovery | 8884cd16-817b-4fba-a564-50a45970baa2 |
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