Ligature-Induced Peri-Implantitis in Minipigs Revisited
dc.accessRights | Anonymous | |
dc.audience | Science | |
dc.contributor.author | Stübinger, Stefan | |
dc.contributor.author | Bucher, Ramon | |
dc.contributor.author | Kronen, Peter | |
dc.contributor.author | Schlottig, Falko | |
dc.contributor.author | von Rechenberg, Brigitte | |
dc.date.accessioned | 2016-03-18T11:11:19Z | |
dc.date.available | 2016-03-18T11:11:19Z | |
dc.date.issued | 2016-02-22 | |
dc.description.abstract | Aim: The ligature-induced defect model still remains the model of first choice to experimentally investigate the cause, effect and treatment approaches of periimplantitis. It was the aim of the present in-vivo trail to revisit the ligature-induced peri-implantitis minipig model regarding its current scientific value and ethical justification in implant research. Materials and methods: Six minipigs were used for the analysis of peri-implant hard and soft tissue structures. Animals were randomly allocated to an experimental silk ligature-induced peri-implantitis group (n=4 animals) and a reference healthy group (n=2 animals). After six weeks mean pocket depths (PD) and bleeding on probing (BOP) measurements were performed just before animals were sacrificed. Results: Overall, ligature-induced peri-implantitis provoked a local inflammation around the experimental implants. Additionally, a loss of crestal bone surrounding the implants could be detected. Mean pocket depths (PD) were 2.2 ± 1.1 mm for healthy animals and 5.4 ± 1.9 mm for peri-implantitis sites. Healthy sites showed a BOP of 60%, whereas peri-implantitis sites disclosed a BOP of 90% within 10 s after probing. Conclusion: Clinical, radiological and histological findings of the present animal experiment supported the overall applicability of the ligature-induced periimplantitis minipig model. A rapid breakdown of peri-implant hard tissues could be detected mainly on the buccal side. | |
dc.description.uri | http://periodontics-prosthodontics.imedpub.com/ligatureinduced-periimplantitis-inminipigs-revisited.php?aid=8443 | |
dc.identifier.issn | 2471-3082 | |
dc.identifier.uri | http://hdl.handle.net/11654/17636 | |
dc.language.iso | en | |
dc.publisher | Prime Scholars | en_US |
dc.relation.ispartof | Periodontics and Prosthodontics | en_US |
dc.title | Ligature-Induced Peri-Implantitis in Minipigs Revisited | |
dc.type | 01A - Beitrag in wissenschaftlicher Zeitschrift | |
dspace.entity.type | Publication | |
fhnw.InventedHere | Yes | |
fhnw.IsStudentsWork | no | |
fhnw.PublishedSwitzerland | Yes | |
fhnw.ReviewType | Anonymous ex ante peer review of a complete publication | |
fhnw.affiliation.hochschule | Hochschule für Life Sciences FHNW | de_CH |
fhnw.affiliation.institut | Institut für Chemie und Bioanalytik | de_CH |
fhnw.publicationOnline | Ja | |
fhnw.publicationState | Published | |
relation.isAuthorOfPublication | c9a2b9dd-53af-4d81-b725-3d252f03e94f | |
relation.isAuthorOfPublication.latestForDiscovery | c9a2b9dd-53af-4d81-b725-3d252f03e94f |
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