Precision and uncertainties for moving targets
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Autor:innen
Autor:in (Körperschaft)
Publikationsdatum
2025
Typ der Arbeit
Studiengang
Typ
04A - Beitrag Sammelband
Herausgeber:innen
Herausgeber:in (Körperschaft)
Betreuer:in
Übergeordnetes Werk
Proton therapy physics
Themenheft
DOI der Originalpublikation
Link
Reihe / Serie
Series in medical physics and biomedical engineering
Reihennummer
Jahrgang / Band
Ausgabe / Nummer
Seiten / Dauer
496-521
Patentnummer
Verlag / Herausgebende Institution
CRC Press
Verlagsort / Veranstaltungsort
Boca Raton
Auflage
3rd Edition
Version
Programmiersprache
Abtretungsempfänger:in
Praxispartner:in/Auftraggeber:in
Zusammenfassung
This chapter discusses time-dependent variations of the target location and the patient's density distribution and its consequences during proton therapy treatments. Variations can occur on different timescales; i.e., over the entire treatment course (weight loss/gain, treatment response of the target), between subsequent treatment fractions (interfractional motion like setup variations or changes in cavity fillings), and within a treatment fraction (intrafractional motion due to heartbeat, breathing, or relaxation). This chapter mainly focuses on intrafractional motion. At the moment, motion in proton radiotherapy is a problem that has not yet been completely solved. A variety of strategies have been discussed to mitigate the effects of motion in proton radiotherapy. The best approach to deal with motion will depend on the tumor sites and the configuration of a specific proton treatment facility, and is likely a combination of strategies discussed in this chapter. First clinical experience indicates that previous in silico studies might have overestimated the dosimetric impact of motion by investigating its effects individually instead of embedded in realistic treatment scenarios. This chapter reviews the research and summarizes the current clinical practice related to the treatment of moving targets with proton therapy.
Schlagwörter
Fachgebiet (DDC)
Veranstaltung
Startdatum der Ausstellung
Enddatum der Ausstellung
Startdatum der Konferenz
Enddatum der Konferenz
Datum der letzten Prüfung
ISBN
978-1-0326-1685-8
ISSN
Sprache
Englisch
Während FHNW Zugehörigkeit erstellt
Ja
Zukunftsfelder FHNW
Publikationsstatus
Veröffentlicht
Begutachtung
Peer-Review der ganzen Publikation
Open Access-Status
Closed
Lizenz
Zitation
Knopf, A., & Meijers, A. (2025). Precision and uncertainties for moving targets. In H. Paganetti (Ed.), Proton therapy physics (3rd Edition, pp. 496–521). CRC Press. https://doi.org/10.1201/9781032616858-27